Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 16/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14114414 | 1.00 | CD38 (0.40) | CD38CCNA2CDK2TRPV1 | |
| SCHEMBL4925482 | 0.80 | CDK2 (0.45) | CCNA2CDK2 | |
| Hydrochloric Acid SCHEMBL4934603 | 0.79 | CDK2 (0.44) | CCNA2CDK2 | |
| SCHEMBL5171705 | 0.74 | HTR4 (0.44) | — | |
| SCHEMBL4930917 | 0.73 | ALDH1A1 (0.46) | — | |
| SCHEMBL13993613 | 0.72 | CDK5 (0.46) | CD38CCNA2CDK2 | |
| SCHEMBL4934115 | 0.71 | PSMD14 (0.31) | — | |
| SCHEMBL4931435 | 0.71 | ANO1 (0.40) | — | |
| SCHEMBL13993717 | 0.69 | CCNA2 (0.37) | CD38CCNA2CDK2 | |
| SCHEMBL13993721 | 0.68 | CCNA2 (0.37) | CD38CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167309-A1 | Pharmaceutical Compounds | ASTEX THERAPEUTICS, LTD. (UK) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167309-A1 | Pharmaceutical Compounds | CCNO, CDK2, CDK1 | CD38 1114/4885CCNA2 9/4885CDK2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.