Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 4/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3679428 | 0.85 | — | — | |
| SCHEMBL4352672 | 0.67 | — | — | |
| SCHEMBL22265048 | 0.63 | — | — | |
| SCHEMBL16178868 | 0.59 | — | — | |
| Hydrogen Peroxide SCHEMBL28709584 | 0.55 | MEN1 (0.60) | CA5ACA5B | |
| Nitric Acid SCHEMBL11611232 | 0.55 | CA5A (0.89) | CA5ACA5B | |
| Nitric Acid SCHEMBL11606188 | 0.55 | CA5A (0.89) | CA5ACA5B | |
| Nitric Acid SCHEMBL29375086 | 0.55 | — | — | |
| Hydrogen Peroxide SCHEMBL28268204 | 0.55 | MEN1 (0.60) | CA5ACA5B | |
| Nitric Acid SCHEMBL338008 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080281094-A1 | Regioselective Functionalisation and Protection of Spirolactams | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2008-11-13 | — | — | US | disclosed |
| US-7297788-B2 | Regioselective hydroxylation, functionalisation and protection of spirolactams | LABORATORIOS DEL DR. ESTEVE. S.A. (ES) | 2007-11-20 | — | — | US | disclosed |
| CN-1976899-A | Regioselective functionalization and protection of spirolactams | ESTEVE LABOR DR (ES) | 2007-06-06 | — | — | CN | disclosed |
| EP-1747197-A1 | REGIOSELECTIVE FUNCTIONALISATION AND PROTECTION OF SPIROLACTAMS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-31 | — | — | EP | disclosed |
| US-20060148778-A1 | Ultraviolet radiation absorbers; such as 1 azaspiro(3,5)nona-5,8-dione derivative substituted in first position with oxy, thio or carbonyl group | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-07-06 | — | — | US | disclosed |
| EP-1676836-A1 | Regioselective hydroxylation, functionalisation and protection of spirolactams II | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-07-05 | — | — | EP | disclosed |
| US-20050261492-A1 | Regioselective hydroxylation, functionalisation and protection of spirolactams | LABORATORIES DEL DR. ESTEVE, S.A. (ES) | 2005-11-24 | — | — | US | disclosed |
| EP-1598336-A1 | Regioselective hydroxylation, functionalisation and protection of spirolactams | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-11-23 | — | — | EP | disclosed |
| WO-2005108357-A1 | REGIOSELECTIVE FUNCTIONALISATION AND PROTECTION OF SPIROLACTAMS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080281094-A1 | Regioselective Functionalisation and Protection of Spirolactams | PAICS, CTSL, GNE | GSR 4292/4885CA5A 2407/4885CA5B 2952/4885 |
| US-20050261492-A1 | Regioselective hydroxylation, functionalisation and protection of spirolactams | POR, CYP51A1, CYP17A1 | GSR 3152/4885CA5A 1522/4885CA5B 2259/4885 |
| US-20060148778-A1 | Ultraviolet radiation absorbers; such as 1 azaspiro(3,5)nona-5,8-dione derivative substituted in first position with oxy, thio or carbonyl group | UNG, OXER1, OGFOD1 | GSR 4253/4885CA5A 484/4885CA5B 757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.