Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.43 |
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | THRA | P10827 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717926 | 0.91 | PTPN1 (0.39) | PTPN1KDM4EMEN1ALDH1A1OPRK1 | |
| SCHEMBL4927550 | 0.89 | THRB (0.53) | PTPN1THRBTHRA | |
| SCHEMBL4357988 | 0.85 | THRA (0.55) | THRBTHRA | |
| SCHEMBL4934576 | 0.85 | KMT2A (0.40) | THRBTHRAKDM4EMEN1ALDH1A1 | |
| SCHEMBL4935259 | 0.85 | THRB (0.39) | THRBTHRAKDM4EMEN1ALDH1A1 | |
| SCHEMBL4932680 | 0.85 | MRGPRX4 (0.42) | PTPN1MEN1ALDH1A1KMT2AMRGPRX4 | |
| SCHEMBL4932229 | 0.82 | PPARD (0.43) | THRBTHRAMRGPRX4RXRB | |
| SCHEMBL5717931 | 0.82 | MRGPRX4 (0.40) | PTPN1MEN1KMT2AMRGPRX4 | |
| SCHEMBL4929427 | 0.82 | THRA (0.47) | THRBTHRAKDM4EMEN1KMT2A | |
| SCHEMBL4930325 | 0.81 | THRA (0.45) | THRBTHRAKMT2AMRGPRX4PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | PTPN1 354/4885THRB 4/4885THRA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.