SCHEMBL4934597

SCHEMBL4934597

Nc1ccc(-c2c3ccccc3c(-c3cccc(N)c3)c3ccccc23)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.54
ACHE P22303 2/20 0.50
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 2/20 0.50
ALDH1A1 P00352 2/20 0.50
LMNA P02545 2/20 0.50
MAPT P10636 2/20 0.50
HPGD P15428 2/20 0.50
KMT2A Q03164 2/20 0.50
GLA P06280 1/20 0.50
CYP3A4 P08684 3/20 0.48
TAAR1 Q96RJ0 2/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
AURKA O14965 1/20 0.46
MAP4K4 O95819 4/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
HSD17B1 P14061 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12337344 0.92 MAOA (0.64) MAOAKDM4EMEN1ALDH1A1LMNA
SCHEMBL4935631 0.92 MAOA (0.62) MAOAKDM4EMEN1ALDH1A1LMNA
SCHEMBL12337342 0.85 TDP1 (0.67) MAOAACHEKDM4EMEN1ALDH1A1
SCHEMBL535035 0.85 ACHE (0.63) MAOAACHEKDM4EMEN1ALDH1A1
SCHEMBL29400302 0.85 ACHE (0.63) MAOAACHEKDM4EMEN1ALDH1A1
SCHEMBL20080558 0.83 ALDH1A1 (0.50) MAOAKDM4EMEN1ALDH1A1LMNA
SCHEMBL26262745 0.83 TDP1 (0.71) MAOAACHEKDM4EMEN1ALDH1A1
SCHEMBL4557173 0.83 TDP1 (0.62) ACHEKDM4EMEN1ALDH1A1MAPT
SCHEMBL28230664 0.82 ALDH1A1 (0.49) MAOAKDM4EMEN1ALDH1A1LMNA
SCHEMBL28010303 0.79 MAOA (0.46) MAOAACHEKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0361377-B1 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1995-06-28 EP claimed
US-4959151-A Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1990-09-25 US claimed
EP-0361377-A2 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-04-04 EP claimed
US-7339009-B2 Cross-linked polyimide and method of making them GENERAL ELECTRIC COMPANY (US) 2008-03-04 US disclosed
US-20060135732-A1 Cross-linked polyimide and method of making them GENERAL ELECTRIC COMPANY 2006-06-22 US disclosed
EP-0361377-B1 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1995-06-28 EP disclosed
US-5292963-A Continuous, polyimide separating membrane UBE INDUSTRIES, LTD. (JP) 1994-03-08 US disclosed
US-4959151-A Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1990-09-25 US disclosed
EP-0361377-A2 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-04-04 EP disclosed