Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198619 | 0.85 | PTPN1 (0.46) | MAPTLMNABCHEALDH1A1GUSB | |
| SCHEMBL31067709 | 0.83 | CA1 (0.56) | AKR1C3MAPTGAABCHEALDH1A1 | |
| SCHEMBL1552369 | 0.83 | CA1 (0.56) | AKR1C3MAPTGAABCHEALDH1A1 | |
| SCHEMBL3651652 | 0.83 | CA1 (0.56) | AKR1C3MAPTGAABCHEALDH1A1 | |
| SCHEMBL31067707 | 0.83 | CA1 (0.56) | AKR1C3MAPTGAABCHEALDH1A1 | |
| SCHEMBL9627381 | 0.80 | MAPT (0.50) | AKR1C3MAPTGAALMNABCHE | |
| SCHEMBL1499959 | 0.80 | RAB9A (0.59) | MAPTLMNABCHENPC1RAB9A | |
| SCHEMBL9496987 | 0.80 | AKR1C3 (0.52) | AKR1C3MAPTGAAALDH1A1ELANE | |
| SCHEMBL2764781 | 0.80 | AKR1C3 (0.52) | AKR1C3MAPTGAAALDH1A1KMT2A | |
| SCHEMBL9497002 | 0.80 | AKR1C3 (0.52) | AKR1C3MAPTGAAALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117778391-A | Novel lithocanol biosynthesis gene promoter of deep sea fungus phomopsis FS508 | 广东省科学院微生物研究所(广东省微生物分析检测中心) | 2024-03-29 | — | — | CN | disclosed |
| WO-2024054950-A1 | CANCER TREATMENT USING MTDP INHIBITORS AND PLK1 INHIBITORS | CARDIFF ONCOLOGY, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| EP-3373971-A1 | METHODS AND COMPOSITIONS FOR DETECTING AND MODULATING CANCER CELLS | Massachusetts Institute of Technology (US) | 2018-09-19 | — | — | EP | disclosed |
| US-20170168056-A1 | METHODS AND COMPOSITIONS FOR DETECTING AND MODULATING CANCER CELLS | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2017-06-15 | — | — | US | disclosed |
| WO-2017083854-A1 | METHODS AND COMPOSITIONS FOR DETECTING AND MODULATING CANCER CELLS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-05-18 | — | — | WO | disclosed |
| US-20080207952-A1 | NOVEL THERAPEUTIC APPLICATIONS OF NATURAL POLY ISOPRENYLATED BENZOPHENONE DERIVATIVES AS DRUGS/MEDICAMENTS | MAJEED MUHAMMED | 2008-08-28 | — | — | US | disclosed |
| US-6956061-B2 | Polyisoprenylbenzophenone derivatives, processes for their preparation and use thereof | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-10-18 | — | — | US | disclosed |
| US-20040082662-A1 | Polyisoprenylbenzophenone derivatives, processes for their preparation and use thereof | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082662-A1 | Polyisoprenylbenzophenone derivatives, processes for their preparation and use thereof | GGPS1, PGGT1B, GNPAT | AKR1C3 1442/4885MAPT 2407/4885GAA 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.