Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067707 | 0.86 | CA1 (0.56) | MAPTGAAAKR1C3PTGS2ALDH1A1 | |
| SCHEMBL3651652 | 0.86 | CA1 (0.56) | MAPTGAAAKR1C3PTGS2ALDH1A1 | |
| SCHEMBL1552369 | 0.86 | CA1 (0.56) | MAPTGAAAKR1C3PTGS2ALDH1A1 | |
| SCHEMBL31067709 | 0.86 | CA1 (0.56) | MAPTGAAAKR1C3PTGS2ALDH1A1 | |
| SCHEMBL9627361 | 0.82 | S100B (0.47) | MAPTPTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL5670612 | 0.81 | HTT (0.42) | MAPTGAAAKR1C3ALDH1A1HSD17B10 | |
| SCHEMBL29263440 | 0.80 | AKR1C3 (0.53) | MAPTGAAAKR1C3ALDH1A1MEN1 | |
| Nitrous Acid SCHEMBL4946660 | 0.80 | CA1 (0.50) | MAPTGAAAKR1C3PTGS2ALDH1A1 | |
| SCHEMBL4934948 | 0.80 | AKR1C3 (0.46) | MAPTGAAAKR1C3ALDH1A1LMNA | |
| SCHEMBL2328371 | 0.79 | NFKB1 (0.50) | MAPTPTPN1LMNABCHEGUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098901-A | Cardiovascular disorders | STERLING DRUG INC. (US) | 1992-03-24 | — | — | US | disclosed |