Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | WNT1 | P04628 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4930087 | 0.85 | KMT2A (0.63) | MDM4CD274HPGDTP53MDM2 | |
| SCHEMBL3943442 | 0.84 | ALDH1A1 (0.47) | MDM4CD274HPGDALDH1A1KDM4E | |
| SCHEMBL4926259 | 0.80 | ALDH1A1 (0.56) | HPGDALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL3950606 | 0.79 | HSD17B10 (0.49) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL5151439 | 0.78 | ALDH1A1 (0.49) | MDM4CD274HPGDTP53MDM2 | |
| SCHEMBL3943840 | 0.78 | ALDH1A1 (0.47) | MDM4CD274HPGDTP53MDM2 | |
| SCHEMBL4926916 | 0.78 | ALDH1A1 (0.53) | HPGDTP53ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL39935 | 0.78 | ALDH1A1 (0.62) | MDM4HPGDTP53MDM2ALDH1A1 | |
| SCHEMBL14307300 | 0.77 | ALDH1A1 (0.46) | MDM4CD274HPGDTP53MDM2 | |
| SCHEMBL14383477 | 0.77 | BACE1 (0.50) | MDM4CD274HPGDTP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004268-A1 | INHIBITORS OF SOLUBLE ADENYLATE CYCLASE | NGUYEN DUY | 2008-01-03 | — | — | US | disclosed |
| US-20060074084-A1 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004268-A1 | INHIBITORS OF SOLUBLE ADENYLATE CYCLASE | ADCY1, ADCY2, ADCY5 | MDM4 4860/4885CD274 4795/4885HPGD 135/4885 |
| US-20060074084-A1 | Inhibitors of soluble adenylate cyclase | ADCY1, ADCY2, ADCY5 | MDM4 4860/4885CD274 4795/4885HPGD 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.