Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | TSHR | P16473 | 7/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19348431 | 0.86 | KMT2A (0.65) | ALDH1A1TSHRALOX15L3MBTL1HTT | |
| SCHEMBL197131 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TSHRALOX15L3MBTL1HTT | |
| SCHEMBL29244538 | 0.84 | USP2 (0.77) | ALDH1A1TSHRALOX15L3MBTL1HTT | |
| SCHEMBL29779557 | 0.84 | TRPV4 (0.57) | ALDH1A1TSHRALOX15L3MBTL1HTT | |
| SCHEMBL6422908 | 0.84 | TSHR (1.00) | ALDH1A1TSHRALOX15L3MBTL1HTT | |
| SCHEMBL30270554 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TSHRALOX15L3MBTL1HTT | |
| SCHEMBL15010830 | 0.82 | TSHR (0.62) | ALDH1A1TSHRALOX15L3MBTL1HTT | |
| SCHEMBL25920392 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TSHRALOX15L3MBTL1HTT | |
| SCHEMBL30270512 | 0.81 | TSHR (0.57) | ALDH1A1TSHRALOX15L3MBTL1HTT | |
| SCHEMBL15651913 | 0.81 | ALDH1A1 (0.73) | ALDH1A1TSHRALOX15L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |