Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29432547 | 0.86 | ALDH1A1 (0.63) | TRPV4ALDH1A1USP2TSHRALOX15 | |
| SCHEMBL493523 | 0.84 | ALDH1A1 (0.74) | TRPV4ALDH1A1USP2HSD11B1TSHR | |
| SCHEMBL29244538 | 0.83 | USP2 (0.77) | TRPV4ALDH1A1USP2HSD11B1TSHR | |
| SCHEMBL19348431 | 0.81 | KMT2A (0.65) | TRPV4ALDH1A1USP2HSD11B1TSHR | |
| SCHEMBL5306092 | 0.77 | MAPT (0.69) | ALDH1A1L3MBTL1HTTPKMLMNA | |
| SCHEMBL25203431 | 0.77 | GRM5 (0.47) | ALDH1A1USP2TSHRALOX15L3MBTL1 | |
| SCHEMBL2959767 | 0.75 | TRPV4 (0.67) | TRPV4ALDH1A1HSD11B1TSHRHPGD | |
| SCHEMBL25207262 | 0.74 | GRM5 (0.43) | ALDH1A1USP2TSHRALOX15L3MBTL1 | |
| SCHEMBL3925070 | 0.74 | KMT2A (0.57) | TRPV4ALDH1A1HSD11B1TSHRHTT | |
| SCHEMBL6445555 | 0.73 | HSD11B1 (0.60) | TRPV4HSD11B1TSHRL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022180443-A1 | GREEN SYNTHESIS, COMPUTER-AIDED DRUG DESIGN, PHYSICOCHEMICAL, AND ADMET PROPERTIES OF NOVEL SULFONAMIDES AS POTENTIAL ANTIMICROBIAL DRUGS | CHINNAM SAMPATH (IN) | 2022-09-01 | — | — | WO | disclosed |