Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL846053 | 0.82 | TRPV1 (0.70) | TRPV1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL846389 | 0.78 | TRPV1 (0.55) | TRPV1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL846529 | 0.74 | TRPV1 (0.67) | TRPV1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL6388258 | 0.71 | TRPV1 (0.47) | TRPV1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL846388 | 0.70 | TRPV1 (0.67) | TRPV1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL847681 | 0.69 | DNMT1 (0.55) | TRPV1SMN1; SMN2MEN1KMT2AHDAC6 | |
| SCHEMBL1749861 | 0.69 | SRD5A2 (0.49) | RAB9ASMN1; SMN2KMT2AKDM4ETP53 | |
| SCHEMBL846060 | 0.69 | TRPV1 (0.72) | TRPV1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL847005 | 0.69 | TRPV1 (0.72) | TRPV1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10154201 | 0.69 | KDM2B (0.63) | TRPV1RAB9ANPC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300236-A1 | QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR | CODD ELLEN | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300236-A1 | QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR | TRPV1, OPRL1, TRPV2 | TRPV1 1/4885RAB9A 2453/4885NPC1 1518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.