Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4935739 | 1.00 | CYP1A2 (0.41) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL9310086 | 0.85 | CES2 (0.42) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL9310089 | 0.85 | CES2 (0.42) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7766368 | 0.80 | SOAT1 (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7766360 | 0.80 | SOAT1 (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7766372 | 0.80 | SOAT1 (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1126715 | 0.80 | APOBEC3A (0.36) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1126713 | 0.80 | APOBEC3A (0.36) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL3533002 | 0.80 | GAA (0.50) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL2914885 | 0.80 | ALDH1A1 (0.46) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227770-A1 | Benzoxazepine Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-18 | — | — | US | disclosed |
| EP-1650201-A1 | BENZOXAZEPINE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2006-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227770-A1 | Benzoxazepine Compound | NR1H2, SQLE, NR1H3 | CYP1A2 63/4885GAA 1705/4885MGAM 2812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.