SCHEMBL49369

SCHEMBL49369

CC1C=CC(C)N1c1ccncc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
MAPT P10636 2/20 0.39
CHKA P35790 1/20 0.38
BCHE P06276 1/20 0.37
USP2 O75604 1/20 0.36
GAA P10253 3/20 0.35
DDAH1 O94760 1/20 0.35
NOS1 P29475 1/20 0.35
ADRB2 P07550 1/20 0.34
NCF1 P14598 1/20 0.34
PLD1 Q13393 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 1/20 0.34
AR P10275 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
NOTUM Q6P988 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507055 0.74 CHKA (0.41) LMNAMAPTCHKABCHEUSP2
SCHEMBL25506006 0.71 HRH3 (0.45) LMNAMAPTCHKABCHEUSP2
SCHEMBL25506008 0.70 ADRB2 (0.42) CHKAADRB2NCF1PLD1
Hydrochloric Acid SCHEMBL25183378 0.69 ADRB2 (0.41) CHKAADRB2NCF1PLD1
SCHEMBL20320110 0.67 CHKA (0.35) LMNACHKABCHEGAAADRB2
SCHEMBL48910 0.62 CHKA (0.59) LMNAMAPTCHKAUSP2GAA
SCHEMBL4120086 0.62 CHKA (0.43) LMNAMAPTCHKABCHEUSP2
Ethane SCHEMBL27940957 0.60 MAPT (0.85) LMNAMAPTCHKAGAADDAH1
SCHEMBL19468905 0.60 CHKA (0.90) MAPTCHKAUSP2GAAADRB2
SCHEMBL17172443 0.60 ALDH1A1 (0.49) LMNAMAPTCHKABCHEUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129136-B2 Kit for performing an assay CYANAGEN SRL (IT) 2012-03-06 US claimed
EP-1962095-B1 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2011-06-15 EP claimed
US-20110053200-A1 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2011-03-03 US claimed
US-7803573-B2 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2010-09-28 US claimed
US-20080241868-A1 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2008-10-02 US claimed
EP-1962095-A1 Method for increasing light emission from a chemiluminescent reaction Cyanagen Srl (IT) 2008-08-27 EP claimed
US-8129136-B2 Kit for performing an assay CYANAGEN SRL (IT) 2012-03-06 US disclosed
EP-1962095-B1 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2011-06-15 EP disclosed
US-20110053200-A1 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2011-03-03 US disclosed
US-7803573-B2 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2010-09-28 US disclosed
US-20080241868-A1 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2008-10-02 US disclosed
EP-1962095-A1 Method for increasing light emission from a chemiluminescent reaction Cyanagen Srl (IT) 2008-08-27 EP disclosed