Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5993941 | 0.92 | CYP4A11 (0.42) | CYP4A11CYP4F2TRPV1MGLLTLR8 | |
| SCHEMBL5991061 | 0.92 | CYP4A11 (0.42) | CYP4A11CYP4F2TRPV1MGLLTLR8 | |
| SCHEMBL4943028 | 0.89 | PTGER4 (0.48) | TRPV1PTGER4PTGER2MAPTALDH1A1 | |
| SCHEMBL4947062 | 0.84 | CYP4A11 (0.45) | CYP4A11CYP4F2MGLLMAPTSMN1; SMN2 | |
| SCHEMBL4941662 | 0.84 | CYP4A11 (0.45) | CYP4A11CYP4F2MGLLTLR8TLR7 | |
| SCHEMBL4946744 | 0.82 | CYP4A11 (0.43) | CYP4A11CYP4F2TRPV1MGLLPTGER4 | |
| SCHEMBL5982493 | 0.81 | PTGER4 (0.48) | TRPV1PTGER4PTGER2MAPTALDH1A1 | |
| SCHEMBL4945322 | 0.79 | CYP4A11 (0.49) | CYP4A11CYP4F2MGLLMAPTSMN1; SMN2 | |
| SCHEMBL5982597 | 0.78 | CYP4A11 (0.44) | CYP4A11CYP4F2MGLLTLR8TLR7 | |
| SCHEMBL11546147 | 0.77 | CYP4A11 (0.50) | CYP4A11CYP4F2TRPV1PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465755-B2 | Hydrazide derivatives as prostaglandin receptors modulators | LABORATOIRES SERONO SA (CH) | 2008-12-16 | — | — | US | disclosed |
| US-20070185191-A1 | Hydrazide derivatives as prostaglandin receptors modulators | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185191-A1 | Hydrazide derivatives as prostaglandin receptors modulators | PTGIR, HPGDS, PGF | CYP4A11 103/4885CYP4F2 386/4885TRPV1 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.