Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945210 | 0.87 | PTGER4 (0.53) | PTGER4PTGER2TBXA2RNR4A2HTR2A | |
| SCHEMBL4944173 | 0.83 | PTGER4 (0.51) | PTGER4PTGER2TBXA2RNR4A2HTR2A | |
| SCHEMBL5982073 | 0.81 | PTGER4 (0.51) | PTGER4PTGER2TBXA2RNR4A2HTR2A | |
| SCHEMBL4940816 | 0.79 | PTGER4 (0.53) | PTGER4PTGER2TBXA2RNR4A2HTR2A | |
| SCHEMBL4937196 | 0.79 | PTGER4 (0.54) | PTGER4PTGER2TBXA2RNR4A2HTR2A | |
| SCHEMBL4937190 | 0.78 | PTGER4 (0.51) | PTGER4PTGER2TBXA2RNR4A2HTR2A | |
| SCHEMBL13992256 | 0.78 | PTGER4 (0.59) | PTGER4PTGER2TBXA2RNR4A2HTR2A | |
| SCHEMBL5990886 | 0.77 | PTGER4 (0.53) | PTGER4PTGER2TBXA2RNR4A2HTR2A | |
| SCHEMBL5982721 | 0.76 | PTGER4 (0.51) | PTGER4PTGER2TBXA2RNR4A2HTR2A | |
| SCHEMBL5982080 | 0.73 | PTGER4 (0.52) | PTGER4PTGER2TBXA2RNR4A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465755-B2 | Hydrazide derivatives as prostaglandin receptors modulators | LABORATOIRES SERONO SA (CH) | 2008-12-16 | — | — | US | disclosed |
| US-20070185191-A1 | Hydrazide derivatives as prostaglandin receptors modulators | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185191-A1 | Hydrazide derivatives as prostaglandin receptors modulators | PTGIR, HPGDS, PGF | PTGER4 18/4885PTGER2 13/4885TBXA2R 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.