Sugi Predict

Sugi Predict / Compounds / Hydroxyamine

Hydroxyamine

Hydroxyamine

SCHEMBL4937262

C[n+]1cccc2ccccc21.NO

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 10/20 0.48
▸ KDM4E B2RXH2 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ APOBEC3A P31941 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ APOBEC3G Q9HC16 1/20 0.43
▸ TERT O14746 1/20 0.42
▸ BCHE P06276 8/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL307903 0.93 ACHE (0.53) ACHEBCHE
SCHEMBL29752612 0.93 ACHE (0.53) ACHEBCHE
Iodide SCHEMBL29462685 0.91 ACHE (0.55) ACHEKDM4EMEN1KMT2ABCHE
Iodide SCHEMBL28357633 0.91 ACHE (0.52) ACHEBCHE
Hydrochloric Acid SCHEMBL30383932 0.91 ACHE (0.52) ACHEBCHE
Bromide SCHEMBL5611688 0.91 ACHE (0.52) ACHEBCHE
Bromide SCHEMBL7776277 0.91 ACHE (0.52) ACHEBCHE
Hydrochloric Acid SCHEMBL2031419 0.91 ACHE (0.52) ACHEBCHE
Iodide SCHEMBL29462677 0.91 ACHE (0.52) ACHEBCHE
Hydrochloric Acid SCHEMBL27855884 0.91 ACHE (0.52) ACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110729-A1 Primary N-hydroxylamines NIH 2004-06-10 — — US claimed
US-20040102420-A1 Primary N-hydroxylamines NIH 2004-05-27 — — US claimed
US-20030153535-A1 Primary N-hydroxylamines THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-08-14 — — US claimed
US-6455589-B1 AN ORALLY ADMINISTRABLE EFFECTIVE UNIT SOLID DOSAGE OF A PRIMARY N-HYDROXYLAMINE OR A SALT, FREE OF NITRONE; USEFUL FOR REDUCING OXIDATIVE DAMAGE OR DELAYING SENESCENCE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-09-24 — — US claimed
WO-2001030979-A1 PRIMARY N-HYDROXYLAMINES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-05-03 — — WO claimed
US-20080268537-A1 PRIMARY N-HYDROXYLAMINES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-10-30 — — US disclosed
US-20040110729-A1 Primary N-hydroxylamines NIH 2004-06-10 — — US disclosed
US-20040102420-A1 Primary N-hydroxylamines NIH 2004-05-27 — — US disclosed
US-20030153535-A1 Primary N-hydroxylamines THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-08-14 — — US disclosed
US-6455589-B1 AN ORALLY ADMINISTRABLE EFFECTIVE UNIT SOLID DOSAGE OF A PRIMARY N-HYDROXYLAMINE OR A SALT, FREE OF NITRONE; USEFUL FOR REDUCING OXIDATIVE DAMAGE OR DELAYING SENESCENCE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-09-24 — — US disclosed
WO-2001030979-A1 PRIMARY N-HYDROXYLAMINES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-05-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030153535-A1 Primary N-hydroxylamines HNMT, NNMT, NAT1 ACHE 626/4885KDM4E 2529/4885MEN1 701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.