⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4938476 | 0.71 | POLB (0.31) | — | |
| SCHEMBL4940596 | 0.68 | POLB (0.31) | — | |
| SCHEMBL4939369 | 0.64 | LMNA (0.36) | — | |
| SCHEMBL13203924 | 0.63 | LMNA (0.30) | — | |
| SCHEMBL14021453 | 0.60 | KDM4E (0.37) | — | |
| SCHEMBL20242568 | 0.58 | TSHR (0.33) | — | |
| SCHEMBL13203925 | 0.58 | LMNA (0.34) | — | |
| SCHEMBL8117407 | 0.58 | LMNA (0.42) | — | |
| SCHEMBL21961915 | 0.57 | CTSD (0.32) | — | |
| SCHEMBL8115022 | 0.57 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021058-A1 | Pyrazolo '3,4-B! Pyridine Compounds And Their Use As Phosphodiesterase Type 4(Pde4) Inhibitors | GLAXO GROUP LIMITED (GB) | 2008-01-24 | — | — | US | disclosed |