Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665873 | 1.00 | DPP4 (0.42) | DPP4ATML3MBTL1KMT2ASLC7A5 | |
| SCHEMBL27564999 | 1.00 | DPP4 (0.42) | DPP4ATML3MBTL1KMT2ASLC7A5 | |
| SCHEMBL28911807 | 0.91 | PTGS2 (0.46) | KMT2ASLC7A5CTSSCTSKMAPT | |
| SCHEMBL28555152 | 0.91 | PTGS2 (0.46) | KMT2ASLC7A5CTSSCTSKMAPT | |
| SCHEMBL28261977 | 0.89 | ATM (0.44) | DPP4ATML3MBTL1KMT2AAAK1 | |
| SCHEMBL28837744 | 0.89 | DPP4 (0.41) | DPP4ATML3MBTL1KMT2ASLC7A5 | |
| SCHEMBL5844667 | 0.87 | KIF11 (0.37) | KMT2ASLC7A5ALDH1A1SMN1; SMN2 | |
| SCHEMBL2844018 | 0.87 | SLC7A5 (0.37) | KMT2ASLC7A5CTSSCTSKSRC | |
| SCHEMBL27513958 | 0.86 | L3MBTL1 (0.47) | DPP4ATML3MBTL1KMT2ASLC7A5 | |
| SCHEMBL25220978 | 0.86 | SMN1; SMN2 (0.38) | DPP4KMT2ASLC7A5CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121396-B | Degradable polydiseleno-containing polydopamine and preparation method and application thereof | 华南理工大学 | 2022-06-10 | — | — | CN | claimed |
| CN-113121396-A | Degradable polydiseleno-containing polydopamine and preparation method and application thereof | 华南理工大学 | 2021-07-16 | — | — | CN | claimed |
| CN-113121396-B | Degradable polydiseleno-containing polydopamine and preparation method and application thereof | 华南理工大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-111018723-B | Preparation and detection method of dapoxetine hydrochloride isomer impurity | 盖天力医药控股集团制药股份有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-113121396-A | Degradable polydiseleno-containing polydopamine and preparation method and application thereof | 华南理工大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-111018723-A | Preparation and detection method of dapoxetine hydrochloride isomer impurity | 盖天力医药控股集团制药股份有限公司 | 2020-04-17 | — | — | CN | disclosed |
| US-10406147-B2 | Piperidine-2, 6-dione derivatives and their use as tumor necrosis factor inhibitors | TIANJIN HEMAY BIO-TECH CO., LTD. (CN) | 2019-09-10 | — | — | US | disclosed |
| US-20190247383-A1 | PIPERIDINE-2, 6-DIONE DERIVATIVES AND THEIR USE AS TUMOR NECROSIS FACTOR INHIBITORS | TIANJIN HEMAY PHARMACEUTICAL CO., LTD. (CN) | 2019-08-15 | — | — | US | disclosed |
| US-10166222-B2 | Piperidine-2, 6-dione derivatives and their use as tumor necrosis factor inhibitors | TIANJIN HEMAY BIO-TECH CO., LTD. (CN) | 2019-01-01 | — | — | US | disclosed |
| US-20180050025-A1 | PIPERIDINE-2, 6-DIONE DERIVATIVES AND THEIR USE AS TUMOR NECROSIS FACTOR INHIBITORS | TIANJIN HEMAY PHARMACEUTICAL CO., LTD. (CN) | 2018-02-22 | — | — | US | disclosed |
| US-9669015-B2 | Piperidine-2, 6-dione derivatives and their use as tumor necrosis factor inhibitors | TIANJIN HEMAY BIO-TECH CO., LTD. (CN) | 2017-06-06 | — | — | US | disclosed |
| CN-101679418-A | [2,6] naphthyridines compounds as protein kinase inhibitors | NOVARTIS AG | 2010-03-24 | — | — | CN | disclosed |
| CN-101597284-A | A kind of preparation method of antineoplastic compound | BEIJING LAIDESAILUSEN PHARMACE (CN) | 2009-12-09 | — | — | CN | disclosed |
| CN-101389609-A | Hydantoin-based kinase inhibitors | HOFFMANN LA ROCHE (CH) | 2009-03-18 | — | — | CN | disclosed |
| CN-101253147-A | Organic compounds | NOVARTIS PHARMA AG (CH) | 2008-08-27 | — | — | CN | disclosed |
| US-20080051432-A1 | PIPERIDINE-2, 6-DIONE DERIVATIVES AND THEIR USE AS TUMOR NECROSIS FACTOR INHIBITORS | TIANJIN HEMAY PHARMACEUTICAL CO., LTD. (CN) | 2008-02-28 | — | — | US | disclosed |
| EP-1867649-A1 | PIPERIDYL-2, 6-DIONE DERIVATIVES USED TO INHIBIT CELLS FROM RELEASING TUMOR NECROSIS FACTOR | Tian Jin Hemay Bio-Tech Co., Ltd. (CN) | 2007-12-19 | — | — | EP | disclosed |
| CN-101023079-A | Substituted hydantoins for the treatment of cancer | HOFFMANN LA ROCHE (CH) | 2007-08-22 | — | — | CN | disclosed |
| CN-1694874-A | Benzodiazepine * derivatives and pharmaceutical compositions containing them | ARROW THERAPEUTICS LTD (GB) | 2005-11-09 | — | — | CN | disclosed |
| CN-1678372-A | Heterocyclic aromatic compounds useful as growth hormone secretagogues | BRISTOL MYERS SQUIBB CO (US) | 2005-10-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180050025-A1 | PIPERIDINE-2, 6-DIONE DERIVATIVES AND THEIR USE AS TUMOR NECROSIS FACTOR INHIBITORS | TNFRSF9, TNFRSF1A, NGFR | DPP4 2779/4885ATM 4800/4885L3MBTL1 3715/4885 |
| US-10406147-B2 | Piperidine-2, 6-dione derivatives and their use as tumor necrosis factor inhibitors | TNF, TNFRSF1A, TNFRSF9 | DPP4 3253/4885ATM 4748/4885L3MBTL1 3964/4885 |
| US-10166222-B2 | Piperidine-2, 6-dione derivatives and their use as tumor necrosis factor inhibitors | TNFRSF1A, TNFRSF9, NGFR | DPP4 2953/4885ATM 4791/4885L3MBTL1 3663/4885 |
| US-20190247383-A1 | PIPERIDINE-2, 6-DIONE DERIVATIVES AND THEIR USE AS TUMOR NECROSIS FACTOR INHIBITORS | TNF, TNFRSF1A, TNFRSF9 | DPP4 3193/4885ATM 4751/4885L3MBTL1 4000/4885 |
| US-20080051432-A1 | PIPERIDINE-2, 6-DIONE DERIVATIVES AND THEIR USE AS TUMOR NECROSIS FACTOR INHIBITORS | TNF, TNFRSF1A, TNFRSF9 | DPP4 3253/4885ATM 4748/4885L3MBTL1 3964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.