SCHEMBL4937596

SCHEMBL4937596

O=C1C(=O)C(c2ccccc2)c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.59
MAPT P10636 3/20 0.59
LMNA P02545 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
MAPK1 P28482 1/20 0.59
HTR2B P41595 1/20 0.59
CYP19A1 P11511 1/20 0.51
ALDH1A1 P00352 1/20 0.46
EDNRB P24530 1/20 0.44
EDNRA P25101 1/20 0.44
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
RAB9A P51151 3/20 0.42
NPC1 O15118 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MAPK10 P53779 1/20 0.42
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
PTGS2 P35354 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29642916 1.00 TP53 (0.59) TP53MAPTLMNACYP1A2CYP3A4
Ethane SCHEMBL28466111 0.96 MAPT (0.55) TP53MAPTLMNACYP1A2CYP3A4
SCHEMBL3135177 0.87 CYP1A2 (0.58) TP53MAPTLMNACYP1A2CYP3A4
SCHEMBL25028023 0.79 LMNA (0.54) TP53MAPTLMNACYP1A2CYP3A4
SCHEMBL29370508 0.77 LMNA (0.54) TP53MAPTLMNACYP1A2CYP3A4
SCHEMBL70993 0.77 LMNA (0.54) TP53MAPTLMNACYP1A2CYP3A4
SCHEMBL25171318 0.77 LMNA (0.54) TP53MAPTLMNACYP1A2CYP3A4
SCHEMBL11099939 0.76 ALDH1A1 (0.45) TP53MAPTLMNACYP1A2CYP3A4
SCHEMBL11415624 0.76 CYP19A1 (0.60) TP53MAPTLMNACYP1A2CYP3A4
SCHEMBL11415626 0.76 CYP19A1 (0.60) TP53MAPTLMNACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109414452-B Cyclodextrins as procoagulants 阿弗隆制药有限公司 2024-02-02 CN claimed
CN-116829168-A Use of cyclosporin analogs as antithrombotic agents 海必恩制药公司 2023-09-29 CN claimed
CN-114728918-B RIP1 inhibitory compounds and methods of making and using the same 里格尔药品股份有限公司 2025-06-17 CN disclosed
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2025-06-05 US disclosed
CN-113416254-B Anti-C5 antibodies with improved pharmacokinetics 瑞颂医药公司 2025-05-09 CN disclosed
CN-115867548-B RIP1K inhibitors 里格尔药品股份有限公司 2025-03-11 CN disclosed
CN-112996519-B Compositions and methods for organ-specific delivery of nucleic acids 德克萨斯大学系统董事会 2025-02-28 CN disclosed
CN-119421870-A Lipid compound and application thereof 传信生物医药(苏州)有限公司 2025-02-11 CN disclosed
CN-119384273-A Organ-specific delivery compositions for nucleic acids 传信生物医药(苏州)有限公司 2025-01-28 CN disclosed
CN-119219587-A Method for preparing phthalide by oxidizing o-xylene 中国石油化工股份有限公司 2024-12-31 CN disclosed
CN-119039128-A Hydroxy naphthoquinone compound for targeted inhibition of vitamin K epoxide reductase and application thereof 哈尔滨医科大学 2024-11-29 CN disclosed
US-20160052982-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2016-02-25 US disclosed
US-7374580-B2 Dyeing compositions comprising A 1,2-indandione derivative L'OREAL S.A. (FR) 2008-05-20 US disclosed
US-7374580-B2 Dyeing compositions comprising A 1,2-indandione derivative L'OREAL S.A. (FR) 2008-05-20 US disclosed
US-20080095838-A1 Solid pharmaceutical composition containing a lipophilic active principle and preparation method thereof CLL PHARMA (FR) 2008-04-24 US disclosed
CN-1329282-A Photographic element with ion exchange compound EASTMAN KODAK CO (US) 2002-01-02 CN disclosed
US-4804684-A ANTICONVULSANTS, ANALGESICS PANMEDICA S.A. (FR) 1989-02-14 US disclosed
EP-0236151-A1 Symmetrically O-disubstituted oximes of benzocondensed beta-diketocycloalkenes, processes for their preparation and their use as medicaments PANMEDICA S.A. (FR) 1987-09-09 EP disclosed
EP-0178903-A2 Improved tellurium imaging composition and film including imide or ammonium salt ENERGY CONVERSION DEVICES, INC. (US) 1986-04-23 EP disclosed
US-3954998-A HERBICIDES UNION CARBIDE CORPORATION (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160052982-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG TP53 1522/4885MAPT 4449/4885LMNA 2571/4885
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG TP53 1522/4885MAPT 4449/4885LMNA 2571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.