Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.38 |
| ▸ | Q9HBH1 | 1/20 | 0.37 | |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GNPAT | O15228 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 4/20 | 0.34 |
| ▸ | MMP3 | P08254 | 4/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4937977 | 1.00 | GPR84 (0.39) | GPR84PLA2G2CPDFMAPK1TP53 | |
| SCHEMBL4940668 | 0.90 | ALDH1A1 (0.34) | GPR84PLA2G2CMAPK1TP53CYP1A2 | |
| SCHEMBL4940673 | 0.90 | ALDH1A1 (0.34) | GPR84PLA2G2CMAPK1TP53CYP1A2 | |
| SCHEMBL4015178 | 0.83 | PLA2G2C (0.36) | GPR84PLA2G2CPDFMAPK1MMP2 | |
| SCHEMBL4014957 | 0.83 | PLA2G2C (0.36) | GPR84PLA2G2CPDFMAPK1MMP2 | |
| SCHEMBL4011599 | 0.83 | DPP7 (0.50) | GPR84PDFCA2 | |
| SCHEMBL4008969 | 0.83 | DPP7 (0.50) | GPR84PDFCA2 | |
| SCHEMBL4009104 | 0.83 | PLA2G2C (0.36) | GPR84PLA2G2CPDFMAPK1MMP2 | |
| SCHEMBL4011308 | 0.83 | DPP7 (0.50) | GPR84PDFCA2 | |
| SCHEMBL4010197 | 0.83 | DPP7 (0.50) | GPR84PDFCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194841-A1 | Preparation of Optically Pure Beta-Amino Acids Having Affinity for the Alpha-Delta Protein | PFIZER INC. | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194841-A1 | Preparation of Optically Pure Beta-Amino Acids Having Affinity for the Alpha-Delta Protein | OPRD1, CHRND, CHRNE | GPR84 705/4885PLA2G2C 1648/4885PDF 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.