Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 5/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | PNCK | Q6P2M8 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.33 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.33 |
| ▸ | WNK2 | Q9Y3S1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2586809 | 0.75 | HTR2C (0.41) | TGFBR1KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL4938134 | 0.74 | APP (0.54) | TLR9 | |
| SCHEMBL4089296 | 0.73 | SLC6A2 (0.36) | ATRNPC1RAB9A | |
| SCHEMBL1202800 | 0.72 | ALDH1A1 (0.49) | CDK5CDK5R1CLK4KDM4ENPC1 | |
| SCHEMBL913532 | 0.71 | APP (0.58) | CDK5CDK5R1KDM4ENPC1PKM | |
| SCHEMBL5048522 | 0.71 | APP (0.58) | DYRK1ACLK1CDK5CDK5R1KDM4E | |
| SCHEMBL24697495 | 0.69 | KDM4E (0.50) | TGFBR1KDM4ENPC1PKMRAB9A | |
| SCHEMBL31540362 | 0.69 | KDM4E (0.50) | TGFBR1KDM4ENPC1PKMRAB9A | |
| SCHEMBL19305211 | 0.69 | KDM4E (0.33) | DYRK1ATGFBR1KDM4ENPC1PKM | |
| SCHEMBL19305214 | 0.68 | TGFBR1 (0.35) | DYRK1ATGFBR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080219922-A1 | Alzheimer's Disease Imaging Agents | EMORY UNIVERSITY | 2008-09-11 | — | — | US | disclosed |
| WO-2007033080-A2 | ALZHEIMER'S DISEASE IMAGING AGENTS | EMORY UNIVERSITY (US) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080219922-A1 | Alzheimer's Disease Imaging Agents | APP, PSEN1, MAPT | DYRK1A 2830/4885FYN 429/4885TGFBR1 3801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.