SCHEMBL493862

SCHEMBL493862

CCOC(=O)CC(O)(C(C)=O)C(=O)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.43
MGAM O43451 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
ALDH1A1 P00352 3/20 0.40
TRPA1 O75762 1/20 0.40
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PKM P14618 2/20 0.39
KDM4E B2RXH2 1/20 0.39
THRB P10828 1/20 0.38
HTT P42858 1/20 0.37
CYP1A2 P05177 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
GSK3A P49840 1/20 0.35
GSK3B P49841 1/20 0.35
CYP4F2 P78329 2/20 0.34
CYP4A11 Q02928 2/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943040 0.84 POLB (0.41) ALDH1A1LMNAHSD17B10PKMKDM4E
SCHEMBL28869251 0.81 ALDH1A1 (0.44) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL22579200 0.81 ALDH1A1 (0.33) ALDH1A1LMNA
SCHEMBL13734750 0.79 GAA (0.39) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL3821286 0.78 ALDH1A1 (0.47) ALDH1A1LMNACYP1A2MEN1KMT2A
SCHEMBL9015635 0.78 GAA (0.44) GAAMGAMSIMGAM2ALDH1A1
Triethyl Citrate SCHEMBL901127 0.77 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1
Triethyl Citrate SCHEMBL23465 0.77 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL27992629 0.77 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1
Triethyl Citrate SCHEMBL5162146 0.76 PKM (0.43) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113785001-A Process for preparing branched polymers of lactic acid 生物价值世界福利公司 2021-12-10 CN claimed
EP-3728394-A1 METHOD TO PREPARE BRANCHED POLYMERS OF LACTIC ACID Bio Valore World S.P.A. Societa' Benefit (IT) 2020-10-28 EP claimed
US-20110280970-A1 ABSORBABLE PUTTY-LIKE IMPLANTS AND METHODS FOR THEIR USE FOR MECHANICAL HEMOSTASIS OF BONE AND FOR THE TREATMENT OF OSSEOUS DEFECTS ORTHOCON, INC. (US) 2011-11-17 US claimed
EP-1677664-A4 ABSORBABLE IMPLANTS AND METHODS FOR THEIR USE IN HEMOSTASIS AND IN THE TREATMENT OF OSSEOUS DEFECTS ORTHOCON INC (US) 2009-08-19 EP claimed
EP-1677708-A1 BIOABSORBABLE PUTTY-LIKE HEMOSTATIC IMPLANTS Orthocon, LLC (US) 2006-07-12 EP claimed
EP-1677664-A2 ABSORBABLE IMPLANTS AND METHODS FOR THEIR USE IN HEMOSTASIS AND IN THE TREATMENT OF OSSEOUS DEFECTS Ortho Therapeutics, LLC. (US) 2006-07-12 EP claimed
US-20060002976-A1 Absorbable putty-like implants and methods for their use for mechanical hemostasis of bone and for the treatment of osseous defects ABYRX, INC. 2006-01-05 US claimed
WO-2005034816-A1 BIOABSORBABLE PUTTY-LIKE HEMOSTATIC IMPLANTS ORTHO THERAPEUTICS, LLC. (US) 2005-04-21 WO claimed
WO-2005034726-A2 ABSORBABLE IMPLANTS AND METHODS FOR THEIR USE IN HEMOSTASIS AND IN THE TREATMENT OF OSSEOUS DEFECTS ORTHO THERAPEUTICS, LLC (US) 2005-04-21 WO claimed
US-20050065214-A1 Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects ABYRX, INC. 2005-03-24 US claimed
CN-113785001-A Process for preparing branched polymers of lactic acid 生物价值世界福利公司 2021-12-10 CN disclosed
EP-3728394-A1 METHOD TO PREPARE BRANCHED POLYMERS OF LACTIC ACID Bio Valore World S.P.A. Societa' Benefit (IT) 2020-10-28 EP disclosed
CN-108473439-A Pyrazolone derivative as nitroxyl donors 卡尔迪奥克斯尔制药公司 2018-08-31 CN disclosed
WO-2016086071-A1 SPECTRALLY ENCODED CONSUMABLE SPECTROMETER APPARATUS AND METHODS NUEOU, INC. (US) 2016-06-02 WO disclosed
CN-103483261-A Preparation method of 1-substitued phenyl-3-carboxymethyl-5-pyrazolone CHINA LUCKY GROUP CORP 2014-01-01 CN disclosed
US-20060013857-A1 Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects ABYRX, INC. 2006-01-19 US disclosed
US-20060002976-A1 Absorbable putty-like implants and methods for their use for mechanical hemostasis of bone and for the treatment of osseous defects ABYRX, INC. 2006-01-05 US disclosed
WO-2005034816-A1 BIOABSORBABLE PUTTY-LIKE HEMOSTATIC IMPLANTS ORTHO THERAPEUTICS, LLC. (US) 2005-04-21 WO disclosed
WO-2005034726-A2 ABSORBABLE IMPLANTS AND METHODS FOR THEIR USE IN HEMOSTASIS AND IN THE TREATMENT OF OSSEOUS DEFECTS ORTHO THERAPEUTICS, LLC (US) 2005-04-21 WO disclosed
US-20050065214-A1 Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects ABYRX, INC. 2005-03-24 US disclosed