⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4941524 | 0.83 | — | — | |
| SCHEMBL4940828 | 0.81 | — | — | |
| SCHEMBL4946659 | 0.79 | ALDH1A1 (0.50) | — | |
| SCHEMBL4943204 | 0.79 | ALDH1A1 (0.50) | — | |
| SCHEMBL9683543 | 0.70 | — | — | |
| SCHEMBL66347 | 0.69 | — | — | |
| SCHEMBL4934417 | 0.69 | — | — | |
| SCHEMBL5651338 | 0.69 | — | — | |
| SCHEMBL28266038 | 0.67 | — | — | |
| SCHEMBL5651341 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110729-A1 | Primary N-hydroxylamines | NIH | 2004-06-10 | — | — | US | claimed |
| US-6455589-B1 | AN ORALLY ADMINISTRABLE EFFECTIVE UNIT SOLID DOSAGE OF A PRIMARY N-HYDROXYLAMINE OR A SALT, FREE OF NITRONE; USEFUL FOR REDUCING OXIDATIVE DAMAGE OR DELAYING SENESCENCE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-09-24 | — | — | US | claimed |
| EP-0672646-B1 | Process for producing beta-nitro-enamines and intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 1998-06-10 | — | — | EP | claimed |
| US-5639895-A | Process for producing β-nitroenamine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | claimed |
| US-5597940-A | REACTING NITROOLEFIN WITH HYDROXYLAMINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-01-28 | — | — | US | claimed |
| EP-0672646-A1 | Process for producing beta-nitro-enamines and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-09-20 | — | — | EP | claimed |
| JP-8081420-A | — | — | None | — | — | JP | disclosed |
| US-20080268537-A1 | PRIMARY N-HYDROXYLAMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-30 | — | — | US | disclosed |
| EP-1744745-A4 | PHARMACEUTICAL NITRONES | CHILDRENS HOSP & RES CT OAK (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1744745-A1 | PHARMACEUTICAL NITRONES | Children's Hospital & Research Center at Oakland (US) | 2007-01-24 | — | — | EP | disclosed |
| US-7026338-B2 | Pharmaceutical nitrones | CHILDREN'S HOSPITAL RESEARCH CENTER AT OAKLAND (US) | 2006-04-11 | — | — | US | disclosed |
| WO-2005110401-A1 | PHARMACEUTICAL NITRONES | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) | 2005-11-24 | — | — | WO | disclosed |
| US-20050256088-A1 | Pharmaceutical nitrones | CHILDREN'S HOSPITAL RESEARCH CENTER AT OAKLAND | 2005-11-17 | — | — | US | disclosed |
| US-6455589-B1 | AN ORALLY ADMINISTRABLE EFFECTIVE UNIT SOLID DOSAGE OF A PRIMARY N-HYDROXYLAMINE OR A SALT, FREE OF NITRONE; USEFUL FOR REDUCING OXIDATIVE DAMAGE OR DELAYING SENESCENCE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-09-24 | — | — | US | disclosed |
| EP-0672646-B1 | Process for producing beta-nitro-enamines and intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5639895-A | Process for producing β-nitroenamine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | disclosed |
| US-5597940-A | REACTING NITROOLEFIN WITH HYDROXYLAMINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-01-28 | — | — | US | disclosed |
| JP-H0881420-A | PRODUCTION OF BETA-NITROENAMINE | SUMITOMO CHEM CO LTD | 1996-03-26 | — | — | JP | disclosed |
| EP-0672646-A1 | Process for producing beta-nitro-enamines and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-09-20 | — | — | EP | disclosed |