SCHEMBL4937597

SCHEMBL4937597

CC(C)Oc1nc(NC(N)=NO)nc(Cl)c1-c1c(F)cc(F)cc1F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5167350 0.87 — —
SCHEMBL5164507 0.81 NPC1 (0.34) —
SCHEMBL4935623 0.71 LMNA (0.42) LMNA
SCHEMBL4938646 0.70 CNR1 (0.33) LMNA
SCHEMBL4939489 0.69 LMNA (0.33) LMNA
SCHEMBL4932061 0.66 MAPT (0.41) LMNA
SCHEMBL5752604 0.61 BCL6 (0.33) —
SCHEMBL10850249 0.60 KMT2A (0.54) LMNA
SCHEMBL4835877 0.58 IDH1 (0.33) —
SCHEMBL29184390 0.58 KMT2A (0.36) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080132522-A1 2-Substituted Pyrimidines, Method for Their Production and Their Use for Controlling Pathogenic Fungi BASF AKTIENGESELLSCHAFT (DE) 2008-06-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080132522-A1 2-Substituted Pyrimidines, Method for Their Production and Their Use for Controlling Pathogenic Fungi TYMS, TYMP, PNPO LMNA 2500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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