Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 5/20 | 0.55 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKLR | P30613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089080 | 0.85 | OXTR (0.57) | OXTRAVPR1AMEN1MAPTPABPC1 | |
| SCHEMBL4939037 | 0.85 | OXTR (0.57) | OXTRAVPR1AMEN1MAPTPABPC1 | |
| SCHEMBL4943160 | 0.84 | OXTR (0.42) | OXTRAVPR1A | |
| SCHEMBL6109720 | 0.82 | OXTR (0.64) | OXTRAVPR1AMEN1MAPTPABPC1 | |
| SCHEMBL4944227 | 0.77 | OXTR (0.60) | OXTRAVPR1AMEN1MAPTKMT2A | |
| SCHEMBL5041532 | 0.77 | OXTR (0.68) | OXTRAVPR1AMEN1KMT2AMMP1 | |
| SCHEMBL5482133 | 0.77 | OXTR (0.68) | OXTRAVPR1AMEN1KMT2AMMP1 | |
| SCHEMBL14492868 | 0.76 | OXTR (0.70) | OXTRAVPR1AMEN1KMT2ALMNA | |
| SCHEMBL14217504 | 0.76 | OXTR (0.70) | OXTRAVPR1AMEN1KMT2ALMNA | |
| SCHEMBL4944228 | 0.74 | OXTR (0.73) | OXTRAVPR1AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167318-A1 | Pharmaceutically active pyrrolidine derivatives | APPLIED RESEARCH SYSTEM ARS HOLDING N.V. (NL) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167318-A1 | Pharmaceutically active pyrrolidine derivatives | OXTR, PRLHR, NR0B1 | OXTR 1/4885AVPR1A 261/4885MEN1 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.