Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL736957 | 0.99 | KDM4E (0.50) | KDM4EKMT2ASMN1; SMN2FOXM1RAB9A | |
| SCHEMBL735913 | 0.98 | KDM4E (0.48) | KDM4EKMT2ASMN1; SMN2FOXM1RAB9A | |
| SCHEMBL737638 | 0.96 | RAB9A (0.46) | KDM4EKMT2ASMN1; SMN2FOXM1RAB9A | |
| SCHEMBL737726 | 0.79 | MAPT (0.48) | KDM4EKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL737545 | 0.77 | MAPT (0.50) | KDM4EKMT2ARAB9AHRH3MAPT | |
| SCHEMBL3216213 | 0.75 | KDM1A (0.61) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL7902701 | 0.75 | FOXM1 (0.53) | KDM4EKMT2ASMN1; SMN2FOXM1HRH3 | |
| SCHEMBL11477736 | 0.74 | FOXM1 (0.65) | KDM4EKMT2ASMN1; SMN2FOXM1RAB9A | |
| SCHEMBL737728 | 0.74 | HRH3 (0.41) | KDM4EKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16046663 | 0.74 | LTA4H (0.62) | KDM4EKMT2ASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101228127-A | Novel Piperidine Derivatives | BANYU PHARMA CO LTD (JP) | 2008-07-23 | — | — | CN | disclosed |
| EP-1892241-A1 | NOVEL PIPERIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-02-27 | — | — | EP | disclosed |