Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL15710162 | 0.92 | ALDH1A1 (0.43) | ALDH1A1THRBTSHR | |
| Ether SCHEMBL4622027 | 0.90 | — | — | |
| Ether SCHEMBL23063642 | 0.88 | ALDH1A1 (0.46) | ALDH1A1THRBTSHRHSD17B10 | |
| Ether SCHEMBL1173072 | 0.87 | ALDH1A1 (0.56) | ALDH1A1THRBTSHRMAPK1 | |
| Ether SCHEMBL5575028 | 0.87 | ALDH1A1 (0.56) | ALDH1A1THRBTSHRMAPK1 | |
| Ether SCHEMBL9639185 | 0.87 | ALDH1A1 (0.56) | ALDH1A1THRBTSHRMAPK1 | |
| Ether SCHEMBL23356828 | 0.87 | ALDH1A1 (0.56) | ALDH1A1THRBTSHRMAPK1 | |
| Ether SCHEMBL15741360 | 0.87 | ALDH1A1 (0.56) | ALDH1A1THRBTSHRMAPK1 | |
| Ether SCHEMBL1419841 | 0.87 | ALDH1A1 (0.56) | ALDH1A1THRBTSHRMAPK1 | |
| Ether SCHEMBL2582269 | 0.87 | ALDH1A1 (0.56) | ALDH1A1THRBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946149-A | Beta-alkyl substituted silane compound, preparation method and application thereof | 武汉大学 | 2024-04-30 | — | — | CN | claimed |
| CN-114456134-B | Alpha-fluoroalkyl substituted cyclopropyl alcohol compound, and preparation method and application thereof | 武汉大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117362358-A | Planar chiral iodo-metallocene, preparation method thereof and method for preparing polysubstituted planar chiral metallocene compound | 武汉大学 | 2024-01-09 | — | — | CN | disclosed |
| CN-113383000-A | Adducts of triphenylphosphine and triphenyl phosphite and their use in bromination of primary alcohols | 法国梅尔基奥材料与生命科学公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-111606950-A | Method for synthesizing silicon-based phosphorus cluster compound and product thereof | 杭州师范大学 | 2020-09-01 | — | — | CN | disclosed |
| US-20080114041-A1 | Benzothiazolesulfonamides | ASTRAZENECA AB (SE) | 2008-05-15 | — | — | US | disclosed |
| EP-1833808-A1 | NEW BENZOTHIAZOLESULFONAMIDES | AstraZeneca AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006068593-A1 | NEW BENZOTHIAZOLESULFONAMIDES | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |
| US-5866705-A | PYROPOLYMERIC CERAMIC | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114041-A1 | Benzothiazolesulfonamides | SULT1E1, TST, SULT1A1 | ALDH1A1 382/4885THRB 2334/4885TSHR 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.