SCHEMBL4941262

SCHEMBL4941262

Cc1cccc(C(C)c2ccccc2)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.49
CYP3A4 P08684 3/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C9 P11712 2/20 0.49
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
CYP2C19 P33261 1/20 0.49
TYR P14679 1/20 0.49
ALDH1A1 P00352 2/20 0.48
LMNA P02545 2/20 0.47
TAAR1 Q96RJ0 1/20 0.47
GABRA1 P14867 3/20 0.43
GABRB2 P47870 3/20 0.43
TSHR P16473 2/20 0.43
TRPA1 O75762 1/20 0.43
FAAH O00519 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3161235 0.88 GABRA1 (0.56) HPGDCYP3A4CYP1A2CYP2C9KMT2A
SCHEMBL17712325 0.87 ESR1 (0.54) HPGDCYP3A4CYP1A2CYP2C9KMT2A
SCHEMBL921042 0.86 ALDH1A1 (0.59) HPGDCYP3A4CYP1A2CYP2C9KMT2A
SCHEMBL1426621 0.82 TYR (0.55) HPGDCYP3A4CYP1A2CYP2C9KMT2A
SCHEMBL3323991 0.82 HPGD (0.50) HPGDCYP3A4CYP1A2CYP2C9KMT2A
SCHEMBL29358402 0.82 ADRA2A (0.47) CYP3A4CYP1A2CYP2C9CYP2C19TYR
SCHEMBL115911 0.82 ADRA2A (0.47) CYP3A4CYP1A2CYP2C9CYP2C19TYR
SCHEMBL29638766 0.81 ACP3 (0.50) CYP3A4CYP2C9CYP2C19TYRLMNA
SCHEMBL28666265 0.81 ACP3 (0.50) CYP3A4CYP2C9CYP2C19TYRLMNA
SCHEMBL710709 0.81 ACP3 (0.50) CYP3A4CYP2C9CYP2C19TYRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101541859-A Poly (arylene ether) copolymer SABIC INNOVATIVE PLASTICS IP (NL) 2009-09-23 CN claimed
US-20080085989-A1 POLY(ARYLENE ETHER) COPOLYMER CITIBANK, N.A., AS COLLATERAL AGENT 2008-04-10 US claimed
WO-2008036454-A1 POLY (ARYLENE ETHER) COPOLYMER SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-03-27 WO claimed
US-20080076884-A1 POLY(ARYLENE ETHER) COMPOSITION AND METHOD CITIBANK, N.A., AS COLLATERAL AGENT 2008-03-27 US claimed
CN-101541859-A Poly (arylene ether) copolymer SABIC INNOVATIVE PLASTICS IP (NL) 2009-09-23 CN disclosed
US-20080085989-A1 POLY(ARYLENE ETHER) COPOLYMER CITIBANK, N.A., AS COLLATERAL AGENT 2008-04-10 US disclosed
WO-2008036454-A1 POLY (ARYLENE ETHER) COPOLYMER SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-03-27 WO disclosed
US-20080076884-A1 POLY(ARYLENE ETHER) COMPOSITION AND METHOD CITIBANK, N.A., AS COLLATERAL AGENT 2008-03-27 US disclosed
US-20080076885-A1 POLY(ARYLENE ETHER) COMPOSITION AND METHOD CITIBANK, N.A., AS COLLATERAL AGENT 2008-03-27 US disclosed
EP-0485207-B1 Stabilized oil-in-water emulsions RHONE POULENC AGROCHIMIE (FR) 1997-05-28 EP disclosed
US-5254344-A Lipophilic pesticide in organic solvent RHONE-POULENC INC. (US) 1993-10-19 US disclosed
US-5206021-A Storage stability, thermostability RHONE-POULENC AG COMPANY (US) 1993-04-27 US disclosed
US-5096711-A Comprising a lipophilic pesticide, solvent, both a hydrophobic and hydrophilic surfactant, a titanium oxide dispersant and water; storage stability; nonmelting solid phase RHONE-POULENC AGROCHIMIE (FR) 1992-03-17 US disclosed
US-4950810-A Selective process for preparting 2,4- or 3,6-di-substituted phenol compounds YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1990-08-21 US disclosed
EP-0335674-A2 Selective process for preparing 2,4- or 3,6-di-substituted phenol compounds YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1989-10-04 EP disclosed
US-4410736-A Coupling of phenols with diphenoquinones THE DOW CHEMICAL COMPANY (US) 1983-10-18 US disclosed
US-3965182-A Preparation of aniline from phenol and ammonia ETHYL CORPORATION (US) 1976-06-22 US disclosed
US-3960962-A AMMONIA, PALLADIUM-PHOSPHINATED POLYSTYRENE RESIN CATALYST ETHYL CORPORATION (US) 1976-06-01 US disclosed
US-3931298-A FROM A HYDROXYAROMATIC AND AMMONIA, GROUP 8-CYCLOHEXANONE CATALYST ETHYL CORPORATION (US) 1976-01-06 US disclosed