Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945322 | 0.83 | CYP4A11 (0.49) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL4937870 | 0.80 | LOXL2 (0.56) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL4946101 | 0.80 | CYP4A11 (0.46) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL15329199 | 0.79 | CYP4A11 (0.62) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL4947062 | 0.79 | CYP4A11 (0.45) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL24835526 | 0.79 | CYP4A11 (0.58) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL70185 | 0.78 | CYP4A11 (0.75) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL24835214 | 0.76 | CYP4A11 (0.58) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL5983170 | 0.76 | CYP4A11 (0.48) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL24835147 | 0.75 | CYP4A11 (0.57) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465755-B2 | Hydrazide derivatives as prostaglandin receptors modulators | LABORATOIRES SERONO SA (CH) | 2008-12-16 | — | — | US | disclosed |
| EP-1654219-A2 | HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005012232-A2 | HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |