Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.57 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CKS1B | P61024 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825792 | 0.86 | CYP4A11 (0.64) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL24835214 | 0.85 | CYP4A11 (0.58) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL15329199 | 0.85 | CYP4A11 (0.62) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL24835526 | 0.84 | CYP4A11 (0.58) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL23423391 | 0.83 | LOXL2 (0.56) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL9826363 | 0.82 | SMN1; SMN2 (0.58) | CYP4A11CYP4F2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL24835146 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL24835207 | 0.81 | CYP4A11 (0.54) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL70185 | 0.80 | CYP4A11 (0.75) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL24835770 | 0.80 | CYP4A11 (0.53) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278698-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |