⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762857 | 0.76 | TSHR (0.39) | — | |
| SCHEMBL27041595 | 0.74 | CTSK (0.42) | — | |
| SCHEMBL27041593 | 0.74 | CTSK (0.42) | — | |
| SCHEMBL29153143 | 0.71 | CTSK (0.31) | — | |
| SCHEMBL4612120 | 0.71 | GPR84 (0.44) | — | |
| SCHEMBL4431785 | 0.71 | — | — | |
| SCHEMBL4970799 | 0.70 | TSHR (0.39) | — | |
| Bicarbonate SCHEMBL29131691 | 0.69 | MAPT (0.38) | — | |
| SCHEMBL1402612 | 0.69 | KDM4E (0.32) | — | |
| SCHEMBL15487288 | 0.68 | SLC6A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480736-A | Hydrophilized polydiorganosiloxane vinyl crosslinkers and uses thereof | 爱尔康公司 | 2021-10-08 | — | — | CN | claimed |
| CN-113613998-B | Packaging solution for contact lenses | 鲍希与洛姆伯股份有限公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-115698776-A | Insert material with high oxygen permeability coefficient and high refractive index | 爱尔康公司 | 2023-02-03 | — | — | CN | disclosed |
| WO-2022270486-A1 | CONTACT LENS AND PRODUCTION METHOD FOR SAID LENS | 日油株式会社 | 2022-12-29 | — | — | WO | disclosed |
| CN-115298573-A | High refractive index silicone insert materials for embedded contact lenses | 爱尔康公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-114981072-A | Wettable silicone hydrogel contact lenses | 爱尔康公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114555649-A | Graft polymers and their use | 博士伦爱尔兰有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114502362-A | Contact lenses with surfaces of varying softness | 爱尔康公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114096567-A | Glycophospholipid polymer networks and uses thereof | 鲍希与洛姆伯股份有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-113613998-A | Packaging solution for contact lenses | 鲍希与洛姆伯股份有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-108369291-B | Method for applying a stable coating on a silicone hydrogel contact lens | 爱尔康公司 | 2021-07-20 | — | — | CN | disclosed |
| CN-108473681-B | Hydrophilized polydiorganosiloxane vinyl crosslinkers and uses thereof | 爱尔康公司 | 2021-07-20 | — | — | CN | disclosed |
| CN-106896422-B | Silicone hydrogel lenses with nanotextured surfaces | 爱尔康公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-112352170-A | Water extractable ophthalmic device | 鲍希与洛姆伯股份有限公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-112041350-A | Ophthalmic devices containing UV blockers and methods of making the same | 鲍希与洛姆伯股份有限公司 | 2020-12-04 | — | — | CN | disclosed |
| CN-106716182-B | Polymerizable polysiloxane with hydrophilic substituent | 爱尔康公司 | 2020-06-12 | — | — | CN | disclosed |
| US-20150153588-A1 | CONTACT LENS WITH SPATIALLY HETEROGENOUS SURFACE PATTERNS FOR IMPROVED LUBRICITY | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2015-06-04 | — | — | US | disclosed |
| WO-2014012016-A1 | CONTACT LENS WITH SPATIALLY HETEROGENEOUS SURFACE PATTERNS FOR IMPROVED LUBRICITY | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-01-16 | — | — | WO | disclosed |
| US-20080002146-A1 | BIOCOMPATIBLE, SURFACE MODIFIED MATERIALS | BAUSCH & LOMB INCORPORATED | 2008-01-03 | — | — | US | disclosed |
| CN-1299387-A | Plasma surface treatment of silicone hydrogel contact lenses | BAUSCH & LUMB INC (US) | 2001-06-13 | — | — | CN | disclosed |