Methacrylic Acid

Methacrylic Acid

SCHEMBL4942155

C=C(C)C(=O)O.C=C(O)Cn1c(=O)n(CC(=C)O)c(=O)n(CC(=C)O)c1=O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 2/20 0.35
HTT P42858 2/20 0.31
MAPT P10636 1/20 0.31
CYP3A4 P08684 1/20 0.30
NPC1 O15118 1/20 0.30
GAA P10253 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536501 0.86 APEX1 (0.38) APEX1CYP3A4
Methacrylic Acid SCHEMBL10441412 0.80 APEX1 (0.32) APEX1CYP3A4
SCHEMBL2362543 0.80 ALDH1A1 (0.32) ALDH1A1
Methacrylic Acid SCHEMBL108959 0.77 APEX1 (0.34) APEX1GAAALDH1A1
Methacrylic Acid SCHEMBL246743 0.77 APEX1 (0.34) APEX1GAAALDH1A1
Methacrylic Acid SCHEMBL248459 0.77 APEX1 (0.34) APEX1GAAALDH1A1
SCHEMBL21176777 0.75 APEX1 (0.39) APEX1MAPTCYP3A4
SCHEMBL18044397 0.74 APEX1 (0.31) APEX1HTTMAPTCYP3A4NPC1
SCHEMBL295471 0.74 HTT (0.46) APEX1HTTCYP3A4ALDH1A1
SCHEMBL23768669 0.71 HTT (0.41) APEX1HTTMAPTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080258345-A1 Liquid Radiation-Curing Compositions STIFTUNG CAESAR (DE) 2008-10-23 US disclosed
US-20070116947-A1 UV-Curing Anti-Fingerprinting Coatings HACKBARTH KARSTEN 2007-05-24 US disclosed
EP-1773901-A1 LIQUID RADIATION-CURING COMPOSITIONS Stiftung CAESAR (DE) 2007-04-18 EP disclosed
WO-2006005772-A1 LIQUID RADIATION-CURING COMPOSITIONS STIFTUNG CAESAR (DE) 2006-01-19 WO disclosed