SCHEMBL2405464

SCHEMBL2405464

O=C(O)CC(C(=O)O)=C(CC(F)(F)F)CC(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.36
FNTB P49356 2/20 0.36
ACLY P53396 2/20 0.35
LDHA P00338 1/20 0.35
SRR Q9GZT4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6053879 0.83 FNTA (0.34) FNTAFNTBACLYLDHASRR
SCHEMBL10886709 0.79 THRB (0.34) FNTAFNTBACLY
SCHEMBL10662248 0.79 FNTA (0.32) FNTAFNTBACLY
SCHEMBL4942932 0.77 THRB (0.41) FNTAFNTB
SCHEMBL9140826 0.75 TET2 (0.34) ACLY
SCHEMBL1791640 0.75 TET2 (0.34) ACLY
SCHEMBL1791642 0.75 TET2 (0.34) ACLY
SCHEMBL10661692 0.74 KDM4E (0.30)
SCHEMBL578968 0.71 LDHA (0.57) FNTAFNTBLDHASRR
SCHEMBL1855287 0.71 LDHA (0.57) FNTAFNTBLDHASRR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
US-8553366-B1 Disk drive with actuator pivot bearing having a surface coating inhibiting lubricant migration WESTERN DIGITAL TECHNOLOGIES, INC. (US) 2013-10-08 US disclosed
US-20120277342-A1 METHACRYLATE-BASED BULKY SIDE-CHAIN SILOXANE CROSS LINKERS FOR OPTICAL MEDICAL DEVICES MCGEE JOSEPH A (US) 2012-11-01 US disclosed
US-8012658-B2 binder resin including a polyester resin and a vinyl resin which the monomer having an alkyloxysilyl group, a wax and a colors; good fixability, durability, noncracking during high speed recording without causing the offset problem RICOH COMPANY LIMITED (JP) 2011-09-06 US disclosed
US-7829254-B2 Non-magnetic toner, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2010-11-09 US disclosed
US-20080220357-A1 TONER FOR DEVELOPING ELECTROSTATIC IMAGE, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE TONER RICOH COMPANY LIMITED (JP) 2008-09-11 US disclosed
US-7344731-B2 Rigid gas permeable lens material BAUSCH & LOMB INCORPORATED (US) 2008-03-18 US disclosed
US-20070218388-A1 NON-MAGNETIC TONER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-09-20 US disclosed
US-20060276605-A1 Rigid gas permeable lens material BAUSCH & LOMB INCORPORATED 2006-12-07 US disclosed
EP-1303258-B1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2006-10-11 EP disclosed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US disclosed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP disclosed
EP-0963398-B1 ORGANIC/INORGANIC COMPOSITES WITH LOW HYDROXYL GROUP CONTENT, METHOD FOR THEIR PRODUCTION AND APPLICATION INST NEUE MAT GEMEIN GMBH (DE) 2002-08-07 EP disclosed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO disclosed
EP-0963398-A1 ORGANIC/INORGANIC COMPOSITES WITH LOW HYDROXYL GROUP CONTENT, METHOD FOR THEIR PRODUCTION AND APPLICATION Institut Für Neue Materialien gem. GmbH (DE) 1999-12-15 EP disclosed
WO-1998037127-A1 ORGANIC/INORGANIC COMPOSITES WITH LOW HYDROXYL GROUP CONTENT, METHOD FOR THEIR PRODUCTION AND APPLICATION INSTITUT FÜR NEUE MATERIALIEN GEM. GMBH (DE) 1998-08-27 WO disclosed
US-4743667-A ACRYLATED SILOXXANES, OXYGEN PERMEABLE NIPPON CONTACT LENS, INC. (JP) 1988-05-10 US disclosed
US-4602074-A SILICON CONTAINING ACRYLIC MONOMER NIPPON CONTACT LENS MANUFACTURING LTD. (JP) 1986-07-22 US disclosed