Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | NEK2 | P51955 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9105334 | 0.90 | CHEK1 (0.39) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL15313276 | 0.90 | MEN1 (0.40) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL9108371 | 0.78 | — | — | |
| SCHEMBL9108861 | 0.78 | — | — | |
| SCHEMBL2720819 | 0.72 | CHEK1 (0.42) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL2724848 | 0.71 | KDM1A (0.32) | — | |
| SCHEMBL15313204 | 0.71 | VCAM1 (0.36) | — | |
| SCHEMBL4947969 | 0.69 | — | — | |
| SCHEMBL15312915 | 0.68 | — | — | |
| SCHEMBL9109244 | 0.68 | HSPB1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012051659-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2012-04-26 | — | — | WO | disclosed |