Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 13/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 12/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 12/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 11/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 11/20 | 0.44 |
| ▸ | MGMT | P16455 | 5/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4946019 | 0.75 | PI4KA (0.47) | PDPK1CDK2MAP3K5LMNACYP1A2 | |
| SCHEMBL2933190 | 0.72 | ADORA1 (0.69) | PDPK1GDAADORA2AADORA1CDK2 | |
| SCHEMBL887880 | 0.72 | PDPK1 (0.51) | PDPK1GDAADORA2AADORA1CDK2 | |
| SCHEMBL4945758 | 0.72 | GDA (0.50) | PDPK1GDACDK2CDK1CCNB1 | |
| 2,6-Diaminopurine SCHEMBL24053 | 0.71 | PDPK1 (1.00) | PDPK1GDAADORA2AADORA1CDK2 | |
| 2,6-Diaminopurine SCHEMBL27891733 | 0.70 | PDPK1 (0.96) | PDPK1GDAADORA2AADORA1CDK2 | |
| 2,6-Diaminopurine SCHEMBL28206545 | 0.70 | PDPK1 (0.96) | PDPK1GDAADORA2AADORA1CDK2 | |
| 2,6-Diaminopurine SCHEMBL8757979 | 0.70 | PDPK1 (0.96) | PDPK1GDAADORA2AADORA1CDK2 | |
| SCHEMBL27691725 | 0.69 | ADORA2A (1.00) | PDPK1GDAADORA2AADORA1CDK2 | |
| 6-Chloroguanine SCHEMBL64059 | 0.68 | DPP4 (1.00) | PDPK1GDAADORA2AADORA1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1895841-A2 | METHODS FOR SELECTIVE N-9 GLYCOSYLATION OF PURINES | Brigham Young University (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006138396-A2 | METHODS FOR SELECTIVE N-9 GLYCOSYLATION OF PURINES | BRIGHAM YOUNG UNIVERSITY, TRANSFER TECHNOLOGY OFFICE (US) | 2006-12-28 | — | — | WO | disclosed |