Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 5/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MGMT | P16455 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750335 | 0.76 | GDA (0.55) | GDAPIK3CAMTORNEK2BRAF | |
| SCHEMBL887125 | 0.76 | GDA (0.55) | GDAPIK3CAMTORNEK2BRAF | |
| SCHEMBL31506448 | 0.76 | GDA (0.55) | GDAPIK3CAMTORNEK2BRAF | |
| SCHEMBL5197101 | 0.75 | GDA (0.54) | GDAPIK3CAMTORNEK2BRAF | |
| SCHEMBL14938904 | 0.75 | GDA (0.54) | GDANEK2PDPK1BRAFKDR | |
| SCHEMBL4943558 | 0.72 | PDPK1 (0.54) | GDAPDPK1MGMTCDK1CCNB1 | |
| SCHEMBL3786829 | 0.69 | GDA (0.44) | GDAPIK3CAMTORNEK2BRAF | |
| SCHEMBL1906545 | 0.69 | — | — | |
| SCHEMBL219478 | 0.67 | GDA (1.00) | GDAKDM4E | |
| SCHEMBL4946019 | 0.67 | PI4KA (0.47) | PDPK1CDC7CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1895841-A2 | METHODS FOR SELECTIVE N-9 GLYCOSYLATION OF PURINES | Brigham Young University (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006138396-A2 | METHODS FOR SELECTIVE N-9 GLYCOSYLATION OF PURINES | BRIGHAM YOUNG UNIVERSITY, TRANSFER TECHNOLOGY OFFICE (US) | 2006-12-28 | — | — | WO | disclosed |