Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.59 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10834671 | 0.86 | ERN1 (0.58) | ERN1PRKDCALDH1A1ABCG2AMY1A | |
| SCHEMBL31663469 | 0.83 | ERN1 (0.66) | ERN1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4374159 | 0.83 | ERN1 (0.66) | ERN1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19867383 | 0.81 | ERN1 (0.42) | ERN1ALDH1A1FNTAFNTBHPGD | |
| SCHEMBL2172189 | 0.80 | ERN1 (0.54) | ERN1PRKDCTSHRALDH1A1HPGD | |
| SCHEMBL12347532 | 0.80 | ERN1 (0.54) | ERN1PRKDCTSHRALDH1A1CYP1A2 | |
| SCHEMBL10163104 | 0.79 | ERN1 (0.57) | ERN1TUBB1PRKDCTSHRALDH1A1 | |
| SCHEMBL28496730 | 0.78 | PTPN1 (0.50) | ALDH1A1HPGDCYP2C19 | |
| SCHEMBL2743917 | 0.76 | ERN1 (0.57) | ERN1TUBB1PRKDCTSHRALDH1A1 | |
| SCHEMBL21823620 | 0.76 | ERN1 (0.57) | ERN1TUBB1PRKDCALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. | 2003-07-03 | — | — | US | claimed |
| CN-113166177-B | Boron-containing PDE4 inhibitors | 辉瑞公司 | 2024-09-03 | — | — | CN | disclosed |
| EP-3861001-B1 | BORON CONTAINING PDE4 INHIBITORS | PFIZER (US) | 2023-12-13 | — | — | EP | disclosed |
| EP-3861001-B1 | BORON CONTAINING PDE4 INHIBITORS | PFIZER (US) | 2023-12-13 | — | — | EP | disclosed |
| US-20230148402-A1 | Boron Containing PDE4 Inhibitors | PFIZER INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230148402-A1 | Boron Containing PDE4 Inhibitors | PFIZER INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230148402-A1 | Boron Containing PDE4 Inhibitors | PFIZER INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-11559538-B2 | Substituted 1,2-oxaborolan-2-ols as PDE4 inhibitors | PFIZER INC. (US) | 2023-01-24 | — | — | US | disclosed |
| US-11559538-B2 | Substituted 1,2-oxaborolan-2-ols as PDE4 inhibitors | PFIZER INC. (US) | 2023-01-24 | — | — | US | disclosed |
| EP-3861001-A1 | BORON CONTAINING PDE4 INHIBITORS | Pfizer Inc. (US) | 2021-08-11 | — | — | EP | disclosed |
| US-8246971-B2 | Compositions containing aromatic aldehydes and their use in treatment | SKINMEDICA, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-20120190753-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | MERZ AESTHETICS, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120157546-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | MERZ AESTHETICS, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20080004354-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENT | CUTANIX CORPORATION | 2008-01-03 | — | — | US | disclosed |
| EP-1299337-A4 | HYDROXYPHENSTATIN AND THE PRODRUGS THEREOF | UNIV ARIZONA STATE (US) | 2004-10-13 | — | — | EP | disclosed |
| US-6777578-B2 | INHIBITOR OF TUBULIN POLYMERIZATION; ANTINEOPLASTIC ACTIVITY | ARIZONA BOARD OF REGENTS | 2004-08-17 | — | — | US | disclosed |
| US-20030220304-A1 | Hydroxyphenstatin and the prodrugs thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-11-27 | — | — | US | disclosed |
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. | 2003-07-03 | — | — | US | disclosed |
| EP-1299337-A1 | HYDROXYPHENSTATIN AND THE PRODRUGS THEREOF | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA acting for and on behalf of ARIZONA STATE UNIVERSITY (US) | 2003-04-09 | — | — | EP | disclosed |
| WO-2001081288-A1 | HYDROXYPHENSTATIN AND THE PRODRUGS THEREOF | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2001-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11559538-B2 | Substituted 1,2-oxaborolan-2-ols as PDE4 inhibitors | PDE4B, PDE4A, PDE3B | ERN1 3025/4885TUBB4A 899/4885TUBB 2041/4885 |
| US-20120190753-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | TYR, ALDH2, AOX1 | ERN1 4597/4885TUBB4A 581/4885TUBB 468/4885 |
| US-20030220304-A1 | Hydroxyphenstatin and the prodrugs thereof | TK1, TUBB8, PHPT1 | ERN1 1210/4885TUBB4A 25/4885TUBB 9/4885 |
| US-20120157546-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | TYR, ALDH2, AOX1 | ERN1 4597/4885TUBB4A 581/4885TUBB 468/4885 |
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | TYR, ALDH2, AOX1 | ERN1 4597/4885TUBB4A 581/4885TUBB 468/4885 |
| US-20080004354-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENT | TYR, ALDH2, AOX1 | ERN1 4634/4885TUBB4A 664/4885TUBB 548/4885 |
| US-20230148402-A1 | Boron Containing PDE4 Inhibitors | PDE4B, PDE4A, PDE3B | ERN1 3340/4885TUBB4A 1010/4885TUBB 1964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.