Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183865 | 1.00 | ADH1C (0.32) | ADH1CADH1AALDH1A1HSD17B10 | |
| SCHEMBL3032794 | 1.00 | ADH1C (0.32) | ADH1CADH1AALDH1A1HSD17B10 | |
| SCHEMBL4940 | 1.00 | — | — | |
| SCHEMBL8185975 | 1.00 | ADH1C (0.32) | ADH1CADH1AALDH1A1HSD17B10 | |
| SCHEMBL8186468 | 1.00 | ADH1C (0.32) | ADH1CADH1AALDH1A1HSD17B10 | |
| SCHEMBL5175 | 1.00 | — | — | |
| SCHEMBL8922 | 0.96 | — | — | |
| SCHEMBL5296 | 0.89 | — | — | |
| SCHEMBL20607552 | 0.82 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL8186496 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 780 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903480-A | Method for preparing beta-enaminone based on sulfoxide and aldoxime and beta-enaminone | 盐城师范学院 | 2023-10-20 | — | — | CN | claimed |
| CN-111233786-B | Benzene sulfonamide compound containing five-membered heterocycle and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-11-26 | — | — | CN | claimed |
| CN-111233786-A | Benzene sulfonamide compound containing five-membered heterocycle and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-06-05 | — | — | CN | claimed |
| US-4284641-A | ANTITHROMBOEMBOLIC AGENT | BURROUGHS WELLCOME CO. (US) | 1981-08-18 | — | — | US | claimed |
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
| EP-3719030-B1 | 19-NOR NEUROACTIVE STEROIDS FOR INDUCING SEDATION | SAGE THERAPEUTICS INC (US) | 2024-07-10 | — | — | EP | disclosed |
| EP-4392432-A2 | POSITIVE NMDA-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | Sage Therapeutics, Inc. (US) | 2024-07-03 | — | — | EP | disclosed |
| CN-113527400-B | 19-NorC 3, 3-disubstituted C21-N-pyrazolyl steroids and methods of use thereof | 萨奇治疗股份有限公司 | 2024-06-28 | — | — | CN | disclosed |
| US-20240199682-A1 | OXYSTEROLS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. | 2024-06-20 | — | — | US | disclosed |
| CN-118206525-A | Aromatic ring [ d ] thiazepine ketone compound and preparation method thereof | 北京化工大学 | 2024-06-18 | — | — | CN | disclosed |
| US-20240182481-A1 | PYRROLO[3,2-D]PYRIMIDINE COMPOUNDS AND METHODS OF USE IN THE TREATMENT OF CANCER | TANGO THERAPEUTICS, INC. | 2024-06-06 | — | — | US | disclosed |
| US-11999727-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2024-06-04 | — | — | US | disclosed |
| EP-0135349-A1 | Condensed seven-membered ring compounds and their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-03-27 | — | — | EP | disclosed |
| EP-0125056-A2 | Condensed, seven-membered ring compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-11-14 | — | — | EP | disclosed |
| US-4482712-A | FUNGICIDES; HERBICIDES; PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1984-11-13 | — | — | US | disclosed |
| EP-0010420-B1 | PYRIDYL-SUBSTITUTED THIAZOLIDINE AND 1,3-THIAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AGRICULTURAL COMPOSITIONS CONTAINING SAID DERIVATIVES AND METHODS FOR REGULATING PLANT GROWTH AND PROTECTING PLANTS FROM FUNGI | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | disclosed |
| US-4436739-A | FUNGICIDES | ELI LILLY AND COMPANY (US) | 1984-03-13 | — | — | US | disclosed |
| EP-0010420-A1 | Pyridyl-substituted thiazolidine and 1,3-thiazine derivatives, processes for their preparation, agricultural compositions containing said derivatives and methods for regulating plant growth and protecting plants from fungi | ELI LILLY AND COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |
| US-4039677-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-08-02 | — | — | US | disclosed |
| US-4038409-A | FUNGICIDES, BACTERICIDES, PROTOZOICIDES | SYNTEX (U.S.A.) INC. (US) | 1977-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11999727-B2 | Compounds and methods of use | F12, C1R, ABCG2 | ADH1C 139/4885ADH1A 215/4885ALDH1A1 128/4885 |
| US-20240199682-A1 | OXYSTEROLS AND METHODS OF USE THEREOF | NR1H3, NR1H2, HSD17B7 | ADH1C 137/4885ADH1A 127/4885ALDH1A1 310/4885 |
| US-20240182481-A1 | PYRROLO[3,2-D]PYRIMIDINE COMPOUNDS AND METHODS OF USE IN THE TREATMENT OF CANCER | DPYD, TYMS, TYMP | ADH1C 396/4885ADH1A 387/4885ALDH1A1 814/4885 |
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | ADH1C 139/4885ADH1A 215/4885ALDH1A1 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.