SCHEMBL4944244

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4946278	0.93	FADS1 (0.55)	FADS1BRAFKITKEAP1SMN1; SMN2
	SCHEMBL4937476	0.86	KIT (0.49)	FADS1BRAFKITSMN1; SMN2NPC1
	SCHEMBL4944485	0.85	KIT (0.58)	FADS1BRAFKITSMN1; SMN2NPC1
	SCHEMBL4941710	0.83	RAB9A (0.46)	BRAFKITSMN1; SMN2NPC1RAB9A
	SCHEMBL4946115	0.83	BRAF (0.48)	FADS1BRAFKITSMN1; SMN2NPC1
	SCHEMBL4945832	0.82	KIT (0.49)	FADS1BRAFKITSMN1; SMN2NPC1
	SCHEMBL31726118	0.79	KIT (0.53)	BRAFKIT
	SCHEMBL4943799	0.79	NPC1 (0.52)	FADS1BRAFKITSMN1; SMN2NPC1
	SCHEMBL4943862	0.77	KIT (0.59)	FADS1BRAFKIT
	SCHEMBL4943390	0.75	KIT (0.79)	BRAFKIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.