Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | F7 | P08709 | 3/20 | 0.50 |
| ▸ | F3 | P13726 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.50 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.50 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | BID | P55957 | 3/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944824 | 1.00 | PPARA (0.53) | PPARAALOX5PTGS2F7F3 | |
| SCHEMBL490157 | 0.93 | PPARA (0.59) | PPARAALOX5PTGS2BIDBCL2L1 | |
| SCHEMBL29580466 | 0.82 | ALOX5 (0.55) | PPARAALOX5PTGS2F7F3 | |
| SCHEMBL1527071 | 0.81 | F7 (0.66) | PPARAF7F3MMP2KDM4E | |
| SCHEMBL1527070 | 0.81 | F7 (0.66) | PPARAF7F3MMP2KDM4E | |
| SCHEMBL489067 | 0.81 | PPARA (0.48) | PPARAALOX5PTGS2F7F3 | |
| SCHEMBL22837454 | 0.80 | ALDH1A1 (0.46) | PPARAALOX5PTGS2 | |
| SCHEMBL27147047 | 0.80 | PPARA (0.85) | PPARAALOX5PTGS2F7F3 | |
| SCHEMBL489248 | 0.79 | PPARA (0.47) | PPARAALOX5PTGS2MAPTSAE1 | |
| SCHEMBL4142804 | 0.79 | PPARA (0.67) | PPARAALOX5PTGS2F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. | 2003-07-03 | — | — | US | claimed |
| US-20180169086-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | ALLERGAN, INC. | 2018-06-21 | — | — | US | disclosed |
| US-9895361-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-20160184289-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | ALLERGAN, INC. | 2016-06-30 | — | — | US | disclosed |
| US-9107874-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-8496951-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2013-07-30 | — | — | US | disclosed |
| US-20130035359-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | ALLERGAN, INC. | 2013-02-07 | — | — | US | disclosed |
| US-8268336-B2 | Compositions containing aromatic aldehydes and their use in treatments | SKINMEDICA, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-8246969-B2 | Use in cosmetics and as topical, transdermal or systemic antiinflammatory pharmaceuticals | SKINMEDICA, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-8246971-B2 | Compositions containing aromatic aldehydes and their use in treatment | SKINMEDICA, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-20120190753-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | MERZ AESTHETICS, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120157546-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | MERZ AESTHETICS, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20080004354-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENT | CUTANIX CORPORATION | 2008-01-03 | — | — | US | disclosed |
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180169086-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | TYR, ALDH2, AOX1 | PPARA 82/4885ALOX5 90/4885PTGS2 497/4885 |
| US-20120190753-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | TYR, ALDH2, AOX1 | PPARA 82/4885ALOX5 90/4885PTGS2 497/4885 |
| US-20130035359-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | TYR, ALDH2, AOX1 | PPARA 82/4885ALOX5 90/4885PTGS2 497/4885 |
| US-20120157546-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | TYR, ALDH2, AOX1 | PPARA 82/4885ALOX5 90/4885PTGS2 497/4885 |
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | TYR, ALDH2, AOX1 | PPARA 82/4885ALOX5 90/4885PTGS2 497/4885 |
| US-20080004354-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENT | TYR, ALDH2, AOX1 | PPARA 82/4885ALOX5 74/4885PTGS2 489/4885 |
| US-20160184289-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | TYR, ALDH2, AOX1 | PPARA 82/4885ALOX5 90/4885PTGS2 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.