Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | SNCA | P37840 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778003 | 0.87 | MAPK14 (0.54) | MAPK14MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL29688279 | 0.86 | ALDH1A1 (0.68) | MAPK14MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL1923372 | 0.86 | ALDH1A1 (0.68) | MAPK14MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL11496557 | 0.85 | MAPK14 (0.56) | MAPK14MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL22852097 | 0.84 | MAPK14 (0.58) | MAPK14MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL4607773 | 0.81 | MAPT (0.86) | MAPK14MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL4225343 | 0.81 | MAPK14 (1.00) | MAPK14MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL28146064 | 0.80 | ALDH1A1 (0.80) | MAPK14MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL22106370 | 0.80 | MAPK14 (0.53) | MAPK14MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL7166997 | 0.79 | MAPT (0.75) | MAPK14MAPTKDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535032-B | Poly-p-phenylethene derivative containing naphthalene ring structure and cyano group and preparation method and application thereof | 黑龙江大学 | 2021-06-25 | — | — | CN | claimed |
| US-5514727-A | OPTICAL FIBER COATINGS, POLYETHER OR POLYESTER POLYOLS ENDCAPPED WITH HYDROXY VINYL ETHER | ALLIEDSIGNAL INC. (US) | 1996-05-07 | — | — | US | claimed |
| CN-109535032-B | Poly-p-phenylethene derivative containing naphthalene ring structure and cyano group and preparation method and application thereof | 黑龙江大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-107148269-B | External preparation composition containing S-flurbiprofen | 大正制药株式会社 | 2020-03-31 | — | — | CN | disclosed |
| CN-105646817-B | Polycarbonate diol, process for producing the same, and polyurethane and active energy ray-curable polymer composition each comprising the same | 三菱化学株式会社 | 2019-08-13 | — | — | CN | disclosed |
| CN-105037683-B | Polyurethane derived from biomass resource, leather, and polyurethane for shoe sole | 三菱化学株式会社 | 2018-11-06 | — | — | CN | disclosed |
| CN-104892884-B | Polyester polyol derived from biomass resource, and polyurethane for leather and shoe sole | 三菱化学株式会社 | 2018-06-12 | — | — | CN | disclosed |
| CN-107108873-A | Polycarbonate resin | 三菱化学株式会社 | 2017-08-29 | — | — | CN | disclosed |
| CN-105452332-B | Method for producing polycarbonate diol, method for producing polyurethane, and polyurethane | 三菱化学株式会社 | 2017-07-14 | — | — | CN | disclosed |
| CN-105646817-A | Polycarbonate diol, process for producing the same, and polyurethane and active energy ray-curable polymer composition each comprising the same | 三菱化学株式会社 | 2016-06-08 | — | — | CN | disclosed |
| CN-102844353-B | Polycarbonate diol, process for producing the same, and polyurethane and active energy ray-curable polymer composition each comprising the same | MITSUBISHI CHEMICAL CORP. (JP) | 2016-02-17 | — | — | CN | disclosed |
| CN-102232092-A | Process for producing polyurethane and use of polyurethane obtained by the process | MITSUBISHI CHEM CORP | 2011-11-02 | — | — | CN | disclosed |
| US-20080161366-A1 | AMINOALKYL SUBSTITUTED ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-07-03 | — | — | US | disclosed |
| CN-1708477-A | Recording material using diphenyl sulfone derivative and novel diphenyl sulfone derivative compound | NIPPON SODA CO (JP) | 2005-12-14 | — | — | CN | disclosed |
| EP-0773977-B1 | COUPLING AGENTS FOR VINYL ETHER-BASED COATING SYSTEMS | ALLIED SIGNAL INC (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0909797-A1 | Stabilizers for vinyl ether-based coating systems | AlliedSignal Inc. (US) | 1999-04-21 | — | — | EP | disclosed |
| US-5672675-A | Vinyl ether-terminated polyester oligomer stabilizers for vinyl ether-based coating systems | ALLIEDSIGNAL, INC. (US) | 1997-09-30 | — | — | US | disclosed |
| US-5539014-A | Adhesion promoters for vinyl ether-based coating systems | ALLIEDSIGNAL INC. (US) | 1996-07-23 | — | — | US | disclosed |
| US-5514727-A | OPTICAL FIBER COATINGS, POLYETHER OR POLYESTER POLYOLS ENDCAPPED WITH HYDROXY VINYL ETHER | ALLIEDSIGNAL INC. (US) | 1996-05-07 | — | — | US | disclosed |
| US-5491178-A | STABILIZING, INHIBITING THE DEHYDROGENATION BY APPLYING A COATING MIXTURE COMPRISING HINDERED PHENOLS, ORGANIC SULFIDES OR DISULFIDES AND TRANSITION METAL SALTS OR COMPLEXES | ALLIEDSIGNAL INC. (US) | 1996-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161366-A1 | AMINOALKYL SUBSTITUTED ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | SLC6A4, SLC6A2, SLC6A3 | MAPK14 601/4885MAPT 97/4885KDM4E 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.