SCHEMBL4945016

SCHEMBL4945016

[C-]#[N+]c1ccc(I)c(Cl)c1Cl

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16180685 0.76 NOTUM (0.48) NOTUM
SCHEMBL9624552 0.71 ALDH1A1 (0.32)
SCHEMBL6505405 0.66 NOTUM (0.52) NOTUM
SCHEMBL11881630 0.64 TSHR (0.31)
SCHEMBL29509555 0.62 NOTUM (0.38) NOTUM
SCHEMBL6563967 0.62 ALDH1A1 (0.39) NOTUM
SCHEMBL17709972 0.62 NOTUM (0.38) NOTUM
SCHEMBL12479120 0.62 NOTUM (0.43) NOTUM
SCHEMBL21839969 0.62 CYP3A4 (0.55) NOTUM
SCHEMBL7124314 0.61 NOTUM (0.52) NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7384749-B2 Electrodes linked via conductive oligomers to nucleic acids CLINICAL MICRO SENSORS, INC. (US) 2008-06-10 US disclosed
US-7381533-B2 Electrodes linked via oligomers to nucleic acids CLINICAL MICRO SENSORS, INC. (US) 2008-06-03 US disclosed
US-7381525-B1 AC/DC voltage apparatus for detection of nucleic acids CLINICAL MICRO SENSORS, INC. (US) 2008-06-03 US disclosed
US-7125668-B2 Electrodes linked via conductive oligomers to nucleic acids CLINICAL MICRO SENSORS, INC. (US) 2006-10-24 US disclosed
US-20060211016-A1 Electrodes linked via conductive oligomers to nucleic acids CLINICAL MICRO SENSORS, INC. 2006-09-21 US disclosed
US-7056669-B2 AC methods for the detection of nucleic acids CLINICAL MICRO SENSORS, INC. (US) 2006-06-06 US disclosed
US-7045285-B1 Electronic transfer moieties attached to peptide nucleic acids CLINICAL MICRO SENSORS, INC. (US) 2006-05-16 US disclosed
US-20060099631-A1 Electrodes linked via oligomers to nucleic acids CLINICAL MICRO SENSORS, INC. 2006-05-11 US disclosed
US-7014992-B1 Conductive oligomers attached to electrodes and nucleoside analogs CLINICAL MICRO SENSORS, INC. (US) 2006-03-21 US disclosed
US-6977151-B2 Electrodes linked via conductive oligomers to nucleic acids CLINICAL MICRO SENSORS, INC. (US) 2005-12-20 US disclosed
US-20030150723-A1 Electrodes linked via conductive oligomers to nucleic acids ROCHE MOLECULAR SYSTEMS, INC. 2003-08-14 US disclosed
US-20030148328-A1 AC methods for the detection of nucleic acids ROCHE MOLECULAR SYSTEMS, INC. 2003-08-07 US disclosed
US-20030003473-A1 Electrodes linked via conductive oligomers to nucleic acids CLINICAL MICRO SENSORS, INC. 2003-01-02 US disclosed
US-6479240-B1 Electrodes linked via conductive oligomers to nucleic acids CLINICAL MICRO SENSORS, INC. 2002-11-12 US disclosed
US-6221583-B1 USE OF NUCLEIC ACIDS CONTAINING ELECTRON TRANSFER MOIETIES TO BE USED AS NUCLEIC ACID PROBES; PROBE NUCLEIC ACID IS COVALENTLY ATTACHED TO AN ELECTRODE VIA A CONDUCTIVE OLIGOMER CLINICAL MICRO SENSORS, INC. 2001-04-24 US disclosed
US-6096273-A SITE-SELECTIVE MODIFICATION OF NUCLEIC ACIDS WITH ELECTRON TRANSFER MOIETIES AND ELECTRODES, FOR GENE PROBES, MEDICAL DIAGNOSIS, TISSUE COMPATIBILITY EVALUATIONS BEFORE TRANSPLANTATION, FORENSICS CLINICAL MICRO SENSORS (US) 2000-08-01 US disclosed
US-6090933-A ATTACHING THE SULFUR OF A CONDUCTIVE OLIGOMER HAVING A FIRST SUBUNIT OF A SULFUR ATOM PROTECTED BY ETHYL PYRIDINE OR TRIMETHYLSILYL ETHYL, TO THE GOLD ELECTRODE; NUCLEIC ACIDS COVALENTLY COUPLED TO ELECTRODES VIA CONDUCTIVE OLIGOMERS CLINICAL MICRO SENSORS, INC. (US) 2000-07-18 US disclosed
US-6063573-A SINGLE-STRANDED PROBE FOR SCREENING TARGET NUCLEOTIDE SEQUENCES CLINICAL MICRO SENSORS, INC. (US) 2000-05-16 US disclosed
EP-0939762-A2 ELECTRODES LINKED VIA CONDUCTIVE OLIGOMERS TO NUCLEIC ACIDS Clinical Micro Sensors (US) 1999-09-08 EP disclosed
WO-1998020162-A2 ELECTRODES LINKED VIA CONDUCTIVE OLIGOMERS TO NUCLEIC ACIDS CLINICAL MICRO SENSORS (US) 1998-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060099631-A1 Electrodes linked via oligomers to nucleic acids POLRMT, APEX1, MTREX NOTUM 4540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.