Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PAFAH1B2 | P68402 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14114232 | 0.90 | CYP2A6 (0.45) | CYP2C9CYP2C19CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL4949975 | 0.86 | RAB9A (0.38) | CYP2C9CYP2C19CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL17088431 | 0.86 | RAB9A (0.38) | CYP2C9CYP2C19CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL13253535 | 0.81 | HTT (0.44) | CYP2C9CYP2C19CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL4452318 | 0.81 | APP (0.57) | CYP2C9CYP2C19CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL11014336 | 0.81 | PTPN1 (0.39) | CYP2C9CYP2C19CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL24040189 | 0.81 | CYP2A6 (0.60) | CYP2C9CYP2C19CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL4948080 | 0.80 | KCNH2 (0.39) | CYP2C9CYP2C19CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL18802998 | 0.80 | ALDH1A1 (0.41) | CYP2C9CYP2C19CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL4950076 | 0.80 | KCNH2 (0.39) | CYP2C9CYP2C19CYP2E1CYP3A4CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188670-A1 | 1,4-Dithienylbenzene Derivative | NAT. INST. OF ADVANCED INDUSTRIAL SCI. AND TECH. (JP) | 2008-08-07 | — | — | US | disclosed |
| US-20080188670-A1 | 1,4-Dithienylbenzene Derivative | NAT. INST. OF ADVANCED INDUSTRIAL SCI. AND TECH. (JP) | 2008-08-07 | — | — | US | disclosed |
| US-20080188670-A1 | 1,4-Dithienylbenzene Derivative | NAT. INST. OF ADVANCED INDUSTRIAL SCI. AND TECH. (JP) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188670-A1 | 1,4-Dithienylbenzene Derivative | SLC22A4, SLC19A2, SLC22A1 | CYP2C9 2167/4885CYP2C19 2262/4885CYP2E1 661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.