SCHEMBL49457

SCHEMBL49457

Cc1cccc([NH])c1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10803005 0.84
SCHEMBL40704 0.77
SCHEMBL5494561 0.77 TRPA1 (0.61)
SCHEMBL294766 0.75
Ammonia Solution, Strong SCHEMBL9810941 0.74 TRPA1 (0.58)
Bromide SCHEMBL21173634 0.74 TRPA1 (0.58)
Benzene SCHEMBL22829865 0.74 TRPA1 (0.58)
Hydrochloric Acid SCHEMBL22194330 0.74 TRPA1 (0.58)
SCHEMBL7695351 0.74 TRPA1 (0.58)
Water SCHEMBL11662813 0.74 TRPA1 (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 520 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112789742-B Organic light emitting device 株式会社LG化学 2024-07-09 CN claimed
CN-112608253-B Organic compound, organic light-emitting element, display device, image pickup device, illumination device, and moving object 佳能株式会社 2024-04-09 CN claimed
CN-117024456-A Condensed cyclic compound, material containing the same, and organic electroluminescent device 中国科学院理化技术研究所 2023-11-10 CN claimed
CN-116019794-A Application of amino fullerene material in preparation of exosome PD-L1 inhibition drugs 中国科学院化学研究所 2023-04-28 CN claimed
CN-115054698-A Cyclodextrin compositions encapsulating selective ATP inhibitors and uses thereof 约翰斯·霍普金斯大学 2022-09-16 CN claimed
CN-112390811-A Dithia-anthrone derivative and preparation method and application thereof 中国科学院理化技术研究所 2021-02-23 CN claimed
CN-110551054-A maleimide derivative, and preparation method and application thereof TECHNICAL INST PHYSICS & CHEMISTRY CAS 2019-12-10 CN claimed
CN-106798740-A A kind of medicine for treating bacterium infection 四川省人民医院 2017-06-06 CN claimed
WO-2009117985-A1 PIRINIXIC ACID DERIVATIVES AS PROSTGLANDIN E2 SYNTHESIS INHIBITORS FOR TREATING INFLAMMATORY DISEASES MEDEON PHARMACEUTICALS GMBH (DE) 2009-10-01 WO claimed
US-20040023890-A1 Drugs for diabetes NICOX S.A. (FR) 2004-02-05 US claimed
EP-0863877-A4 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INST (US) 1999-07-21 EP claimed
US-5874443-A BIOSYNTHESIS TREGA BIOSCIENCES, INC. (US) 1999-02-23 US claimed
EP-0863877-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1998-09-16 EP claimed
WO-1997016428-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1997-05-09 WO claimed
US-4800201-A 1,4-thiazine derivative, and cardiotonic agent comprising it as effective component ZENYAKU KOGYO KABUSHIKI KAISHA (JP) 1989-01-24 US claimed
EP-0087709-A1 N,N',N\"-triaryl-1,2,3-triaminopropane derivatives, process for their preparation and their use as intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1983-09-07 EP claimed
US-4341551-A HERBICIDES, FUNGICIDES, PLANT GROWTH REGULATORS SCHERING AG (DE) 1982-07-27 US claimed
US-4248869-A FUNGICIDES SHIONOGI & CO., LTD. (JP) 1981-02-03 US claimed
US-4228165-A AGRICULTURAL FUNGICIDES SHIONOGI & CO., LTD. (JP) 1980-10-14 US claimed
US-3980685-A Magnesium-aluminum containing complexes of organic anions of central nervous system affecting compounds KYOWA CHEMICAL INDUSTRY CO., LTD. (JA) 1976-09-14 US claimed