Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12914639 | 0.91 | DGAT1 (0.35) | DGAT1CA2CA12CA14CYP2D6 | |
| SCHEMBL3821975 | 0.86 | DGAT1 (0.40) | DGAT1CA2CA12CA14CYP2D6 | |
| SCHEMBL6688426 | 0.81 | DGAT1 (0.37) | DGAT1CA2CA12CA14CYP2D6 | |
| SCHEMBL12914654 | 0.81 | STING1 (0.33) | DGAT1CA2CA12CA14HDAC3 | |
| SCHEMBL16256491 | 0.80 | GAA (0.33) | TSHRGAA | |
| SCHEMBL12234254 | 0.80 | DGAT1 (0.34) | DGAT1CA2CA12CA14CYP2D6 | |
| SCHEMBL27639930 | 0.79 | HDAC3 (0.38) | DGAT1CA2CA12CA14CYP2D6 | |
| SCHEMBL5547017 | 0.79 | DGAT1 (0.36) | DGAT1CA2CA12CA14CYP2D6 | |
| SCHEMBL15160845 | 0.78 | ALDH1A1 (0.40) | TSHRTDP1 | |
| SCHEMBL23451362 | 0.78 | DGAT1 (0.33) | DGAT1CA2CA12CA14CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132496-A1 | CARBOXYLIC ACID AMIDES, THE PREPARATION THEREOF, AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2008-06-05 | — | — | US | claimed |
| US-20040220169-A1 | Carboxylic acid amides, the preparation thereof, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-11-04 | — | — | US | claimed |
| US-20250243319-A1 | STRONG BINDING METAL-CHELATING RESINS USING MACROCYCLE MOLECULES | SACHEM INC (US) | 2025-07-31 | — | — | US | disclosed |
| US-12331155-B2 | Strong binding metal-chelating resins using macrocycle molecules | SACHEM, INC. (US) | 2025-06-17 | — | — | US | disclosed |
| US-20230365514-A1 | MACROCYCLIC COMPOUNDS | NOVO NORDISK RESEARCH CENTRE OXFORD LIMITED (GB) | 2023-11-16 | — | — | US | disclosed |
| US-20220380520-A1 | STRONG BINDING METAL-CHELATING RESINS USING MACROCYCLE MOLECULES | SACHEM, INC. | 2022-12-01 | — | — | US | disclosed |
| WO-2022235769-A1 | STRONG BINDING METAL-CHELATING RESINS USING MACROCYCLE MOLECULES | SACHEM, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| CN-104007629-B | Liquid developer, image forming apparatus and method, developer box and handle box | 富士施乐株式会社 | 2019-11-29 | — | — | CN | disclosed |
| CN-105527807-B | Toner for developing electrostatic latent image | 柯尼卡美能达株式会社 | 2019-11-05 | — | — | CN | disclosed |
| CN-105527805-B | Electrostatic image developing toner | Koyanagi Miyoshi (JP) | 2019-11-01 | — | — | CN | disclosed |
| CN-105045056-B | Image forming method | 柯尼卡美能达株式会社 | 2019-10-18 | — | — | CN | disclosed |
| CN-1013201-B | PROCESSES OF BULK POLYMERIZATION FOR PREPARING POLYMERS OR COPOLYMERS BASED ON CHLORO ETHELENE | ATOCHEM (FR) | 1991-07-17 | — | — | CN | disclosed |
| CN-1009004-B | Vinyl chloride copolymer and process for producing the same | ATOCHEM (FR) | 1990-08-01 | — | — | CN | disclosed |
| CN-88100289-A | With vinylchlorid is the mass polymerization production method of the polymkeric substance and the multipolymer of main component | — | 1988-12-07 | — | — | CN | disclosed |
| US-RE32491-E | BACTERICIDES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1987-09-01 | — | — | US | disclosed |
| CN-87100379-A | vinyl chloride copolymer and preparation method thereof | — | 1987-08-05 | — | — | CN | disclosed |
| US-4414153-A | 1,3-Dithietane-2-carboxylic acid penicillin and cephalosporin derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1983-11-08 | — | — | US | disclosed |
| US-4404373-A | Process for the preparation of 7α-methoxy-7β-(1,3-diethietane-2-carboxamido)cephalosporanic acid derivatives | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-09-13 | — | — | US | disclosed |
| US-4263432-A | ANTIBIOTICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-04-21 | — | — | US | disclosed |
| US-4198339-A | INTERMEDIATES FOR PENICILLINS AND CEPHALOSPORINS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1980-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132496-A1 | CARBOXYLIC ACID AMIDES, THE PREPARATION THEREOF, AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | F12, F11, F2 | DGAT1 3377/4885CA2 162/4885CA12 173/4885 |
| US-20040220169-A1 | Carboxylic acid amides, the preparation thereof, and their use as pharmaceutical compositions | F12, F11, F2 | DGAT1 2018/4885CA2 107/4885CA12 261/4885 |
| US-20230365514-A1 | MACROCYCLIC COMPOUNDS | SLC2A4, GALE, MPI | DGAT1 2615/4885CA2 554/4885CA12 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.