Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319838 | 1.00 | CA12 (0.40) | CA12CA1CA9CA2MAPK1 | |
| SCHEMBL163902 | 0.91 | ACE2 (0.46) | ACE2GPR84FFAR1PPARDMAPT | |
| SCHEMBL740194 | 0.91 | ACE2 (0.46) | ACE2GPR84FFAR1PPARDMAPT | |
| SCHEMBL4945136 | 0.90 | ALDH1A1 (0.34) | CA12CA1CA9CA2MAPK1 | |
| SCHEMBL6673311 | 0.90 | ACE2 (0.44) | ACE2GPR84FFAR1PPARDMAPT | |
| Hydrochloric Acid SCHEMBL4941451 | 0.89 | CA12 (0.33) | CA12CA1CA9CA2MAPK1 | |
| SCHEMBL11634475 | 0.82 | GPR84 (0.46) | ACE2GPR84FFAR1PPARDMAPT | |
| SCHEMBL10982866 | 0.82 | GPR84 (0.46) | ACE2GPR84FFAR1PPARDMAPT | |
| SCHEMBL28106316 | 0.82 | GPR84 (0.41) | CA2MAPK1ACE2GPR84FFAR1 | |
| SCHEMBL28856644 | 0.82 | MMP1 (0.42) | CA12CA1CA9CA2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080071094-A1 | Process for the preparation of perindopril | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-20 | — | — | US | disclosed |
| US-7291745-B2 | Process for the preparation of perindopril | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-11-06 | — | — | US | disclosed |
| WO-2007085933-A2 | PROCESS FOR THE PREPARATION OF N-[1-(S)-ETHOXYCARBONYL-1-BUTYL]-(S)-ALANINE-DMT COMPLEX AND ITS USE IN THE PREPARATION OF PERINDOPRIL | GLENMARK PHARMACEUTICALS LIMITED (US) | 2007-08-02 | — | — | WO | disclosed |
| US-20060211867-A1 | Process for the preparation of perindopril | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211867-A1 | Process for the preparation of perindopril | ACE, PRSS1, CYP2S1 | CA12 3514/4885CA1 2893/4885CA9 2772/4885 |
| US-20080071094-A1 | Process for the preparation of perindopril | ACE, PRSS1, CYP2S1 | CA12 3514/4885CA1 2893/4885CA9 2772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.