Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16081598 | 0.85 | MAPT (0.53) | KMT2ATLR9ATMMAPTMEN1 | |
| SCHEMBL5551222 | 0.82 | HTR3A (0.47) | KMT2ATLR9ATMMAPTMEN1 | |
| SCHEMBL29903456 | 0.81 | KMT2A (0.67) | KMT2ATLR9ATMMAPTMEN1 | |
| SCHEMBL5803173 | 0.81 | KMT2A (0.67) | KMT2ATLR9ATMMAPTMEN1 | |
| SCHEMBL13156573 | 0.80 | MYC (0.48) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL13156555 | 0.79 | MYC (0.59) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL29922808 | 0.78 | KMT2A (0.67) | KMT2ATLR9ATMMAPTMEN1 | |
| SCHEMBL3480837 | 0.78 | KMT2A (0.67) | KMT2ATLR9ATMMAPTMEN1 | |
| SCHEMBL4586206 | 0.78 | KMT2A (0.67) | KMT2ATLR9ATMMAPTMEN1 | |
| SCHEMBL732274 | 0.78 | MAPT (0.56) | KMT2AATMMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140080824-A1 | STRUCTURE-GUIDED IDENTIFICATION OF BINDING INTERACTIONS OF HUMAN LAMININ RECEPTOR PRECURSOR WITH LAMININ AND IDENTIFICATION OF COMPOUNDS THAT AFFECT BINDING | NEW YORK UNIVERSITY (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140080824-A1 | STRUCTURE-GUIDED IDENTIFICATION OF BINDING INTERACTIONS OF HUMAN LAMININ RECEPTOR PRECURSOR WITH LAMININ AND IDENTIFICATION OF COMPOUNDS THAT AFFECT BINDING | NEW YORK UNIVERSITY (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140080824-A1 | STRUCTURE-GUIDED IDENTIFICATION OF BINDING INTERACTIONS OF HUMAN LAMININ RECEPTOR PRECURSOR WITH LAMININ AND IDENTIFICATION OF COMPOUNDS THAT AFFECT BINDING | NEW YORK UNIVERSITY (US) | 2014-03-20 | — | — | US | disclosed |
| WO-2012054739-A2 | STRUCTURE-GUIDED IDENTIFICATION OF BINDING INTERACTIONS OF HUMAN LAMININ RECEPTOR PRECURSOR WITH LAMININ AND IDENTIFICATION OF COMPOUNDS THAT AFFECT BINDING | NEW YORK UNIVERSITY (US) | 2012-04-26 | — | — | WO | disclosed |
| EP-0585873-B1 | Method of preparing disazo pigments | CLARIANT GMBH (DE) | 1997-12-29 | — | — | EP | disclosed |
| US-5559216-A | AZO COUPLING | HOECHST AG (DE) | 1996-09-24 | — | — | US | disclosed |
| US-5493011-A | PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS | HOECHST AG (DE) | 1996-02-20 | — | — | US | disclosed |
| EP-0518909-B1 | WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE | HOECHST AG (DE) | 1994-05-25 | — | — | EP | disclosed |
| EP-0585873-A1 | Method of preparing disazo pigments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-09 | — | — | EP | disclosed |
| EP-0316649-B1 | WATER INSOLUBLE AZO COLOURING AGENTS, THEIR PREPARATION AND USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-22 | — | — | EP | disclosed |
| EP-0316649-A2 | Water insoluble azo colouring agents, their preparation and use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-24 | — | — | EP | disclosed |
| US-4064127-A | Trifluoromethyl dibenzo[a,c]phenazines as immune regulants | ELI LILLY AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-4024142-A | 9-(TRIFLUOROMETHYL)ACENAPHTHO(1,2-B) QUINOXALINE | ELI LILLY AND COMPANY (US) | 1977-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080824-A1 | STRUCTURE-GUIDED IDENTIFICATION OF BINDING INTERACTIONS OF HUMAN LAMININ RECEPTOR PRECURSOR WITH LAMININ AND IDENTIFICATION OF COMPOUNDS THAT AFFECT BINDING | LAMTOR3, L1CAM, AGER | KMT2A 4403/4885TLR9 2057/4885ATM 3873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.