Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546248 | 0.87 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL29777509 | 0.86 | LMNA (0.53) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL545449 | 0.86 | LMNA (0.53) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL22712682 | 0.85 | LMNA (0.67) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL4248747 | 0.84 | LMNA (0.48) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL3185946 | 0.83 | MAPT (0.46) | ALDH1A1MAPTNCF1 | |
| SCHEMBL18775237 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL18783072 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL21416852 | 0.80 | LMNA (0.42) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL16217385 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089034-A2 | CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008089034-A2 | CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-07-24 | — | — | WO | disclosed |