⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3060862 | 0.81 | — | — | |
| SCHEMBL5052464 | 0.79 | — | — | |
| SCHEMBL848820 | 0.79 | — | — | |
| SCHEMBL29281945 | 0.79 | CHRNB2 (0.41) | — | |
| SCHEMBL28774627 | 0.74 | CHRNB2 (0.42) | — | |
| SCHEMBL6849820 | 0.74 | CHRNB2 (0.41) | — | |
| SCHEMBL11057740 | 0.74 | ALDH1A1 (0.41) | — | |
| SCHEMBL1781537 | 0.73 | — | — | |
| SCHEMBL28257547 | 0.73 | L3MBTL1 (0.45) | — | |
| SCHEMBL38507 | 0.73 | L3MBTL1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109694343-B | Decarboxylation method of heterocyclic carboxylic acid compounds | 帕潘纳(北京)科技有限公司 | 2020-07-28 | — | — | CN | claimed |
| CN-109694343-A | A kind of heterocyclic carboxylic acid class compound it is decarboxylation method used | 帕潘纳(北京)科技有限公司 | 2019-04-30 | — | — | CN | claimed |
| CN-118191258-B | Method for identifying key high-toxicity disinfection byproducts in drinking water by taking genotoxicity as guide | 同济大学 | 2024-09-10 | — | — | CN | disclosed |
| CN-118191258-A | Method for identifying key high-toxicity disinfection byproducts in drinking water by taking genotoxicity as guide | 同济大学 | 2024-06-14 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-109694343-B | Decarboxylation method of heterocyclic carboxylic acid compounds | 帕潘纳(北京)科技有限公司 | 2020-07-28 | — | — | CN | disclosed |
| CN-109694343-A | A kind of heterocyclic carboxylic acid class compound it is decarboxylation method used | 帕潘纳(北京)科技有限公司 | 2019-04-30 | — | — | CN | disclosed |
| EP-1937682-B1 | MET KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-08-12 | — | — | EP | disclosed |
| US-7547782-B2 | Met kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547782-B2 | Met kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-06-16 | — | — | US | disclosed |
| US-7435750-B2 | Method of using substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| EP-1406632-A2 | SUBSTITUTED 3-ARYL-5-ARYL- 1,2,4]-OXADIAZOLES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | Cytovia, Inc. (US) | 2004-04-14 | — | — | EP | disclosed |
| US-20030045546-A1 | Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2003-03-06 | — | — | US | disclosed |
| WO-2002100826-A2 | SUBSTITUTED 3-ARYL-5-ARYL-[1,2,4]-OXADIAZOLES AND ANALOGS | CYTOVIA, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| CN-1058490-C | Tetrazolinone derivatives | BAYER AGROCHEM KK (JP) | 2000-11-15 | — | — | CN | disclosed |
| EP-0695748-B1 | Tetrazolinone herbicides | BAYER AGROCHEM KK (JP) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997013512-A1 | N-[2-SUBSTITUTED-3-(2-AMINOETHYL)-1H-INDOL-5-YL]-AMIDES: NEW 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1997-04-17 | — | — | WO | disclosed |
| US-5589439-A | HERBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1996-12-31 | — | — | US | disclosed |
| CN-1122333-A | Tetrazolinone derivatives | BAYER AGROCHEM KK (JP) | 1996-05-15 | — | — | CN | disclosed |
| EP-0695748-A1 | Tetrazolinone herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1996-02-07 | — | — | EP | disclosed |