Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | CD44 | P16070 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596451 | 0.79 | TRPA1 (0.46) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL30314457 | 0.79 | TRPA1 (0.46) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL11593372 | 0.79 | TSHR (0.47) | CYP2A6CYP1A2TSHRACHEALDH1A1 | |
| SCHEMBL29479067 | 0.77 | TRPA1 (0.50) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL9109699 | 0.77 | TRPA1 (0.44) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL309076 | 0.77 | TRPA1 (0.50) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL12270904 | 0.73 | TRPA1 (0.46) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL5951494 | 0.71 | TRPA1 (0.39) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL40704 | 0.71 | — | — | |
| SCHEMBL5494561 | 0.71 | TRPA1 (0.61) | TRPA1ATMCYP2A6CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7438981-B2 | Indenofluorene compounds and organic electroluminescent devices using the same | LG. PHILIPS LCD CO., LTD. (KR) | 2008-10-21 | — | — | US | disclosed |
| US-20070141389-A1 | Indenofluorene compounds and organic electroluminescent devices using the same | LG.PHILIPS LCD CO., LTD. (KR) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070141389-A1 | Indenofluorene compounds and organic electroluminescent devices using the same | KCNH2, KCNH3, KCNJ2 | TRPA1 147/4885ATM 3326/4885CYP2A6 3047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.