Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950460 | 0.90 | VCAM1 (0.42) | VCAM1ALDH1A1LMNAXDHGAA | |
| SCHEMBL5077502 | 0.86 | ALDH1A1 (0.43) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL8140554 | 0.81 | VCAM1 (0.60) | VCAM1ALDH1A1LMNAXDHGAA | |
| SCHEMBL4953419 | 0.80 | PTGS1 (0.39) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL4948327 | 0.79 | STS (0.49) | ALDH1A1GAAKDM4E | |
| SCHEMBL4950454 | 0.78 | PTGS1 (0.50) | — | |
| SCHEMBL4948367 | 0.78 | ESR2 (0.43) | MEN1KMT2A | |
| SCHEMBL4667310 | 0.76 | VCAM1 (0.54) | VCAM1ALDH1A1LMNAXDHGAA | |
| SCHEMBL9373575 | 0.76 | VCAM1 (0.54) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL7023145 | 0.76 | VCAM1 (0.57) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |